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2 Star Hotels in Southeast Missouri, Missouri

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Check availability on Southeast Missouri 2 Star Hotels

Tonight
27 Aug - 28 Aug
Tomorrow
28 Aug - 29 Aug
This weekend
28 Aug - 30 Aug
Next weekend
4 Sept - 6 Sept

Our top choices for Southeast Missouri 2-star hotels

A dining area with tables and chairs, a kitchen area, and a TV mounted on the wall.
A parking lot with a tree in bloom, a red fire hydrant, and a building in the background.
A gym with cardio equipment, a bench press, and a squat rack.
A hotel reception area with a glass partition, a reception desk, and a digital kiosk.

1. Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
Farmington
United States
ILUNGA
€56
includes taxes & fees
6 Sept - 7 Sept
Baymont Inn and Suites by Wyndham Farmington, MO
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.
A multi-story hotel with a mix of brick and red facade, featuring a Holiday Inn Express sign.
Two patterned armchairs, a small round table with a lamp, and a staircase with decorative railings.

2. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
United States
ELAINE
€96
includes taxes & fees
27 Sept - 28 Sept
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A hotel lobby with a reception desk, two red armchairs, a floral centerpiece, a framed cityscape picture, and a dining area in the background.
A hotel room with a living area, kitchenette, and a desk with a computer and chair.
A hotel room with a shower, a bathtub, a toilet, a bed, a desk, a chair, and a television.
A hotel lobby with a reception desk, two red armchairs, a coffee table, a floral centerpiece, and a dining area with wooden tables and chairs.

3. Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South
Festus
United States
Clyde
€61
includes taxes & fees
20 Sept - 21 Sept
Comfort Inn Festus - St Louis South
A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.
A hotel room with two beds, a desk, a chair, a TV mounted on the wall, and a mirror.
A motel with a prominent '66' sign, large windows, and a flat roof.
A hotel reception area with a modern design, featuring a reception desk, a glass door, and a wall with framed pictures and a large number '6' sign.

4. Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
Poplar Bluff
United States
Kathleen
€76
includes taxes & fees
28 Aug - 29 Aug
Motel 6 Poplar Bluff, MO
A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.
A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.
A spacious room with a large dining table and chairs, a kitchenette area, and a television mounted on the wall.

5. Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
Sikeston
United States
Lori
€64
includes taxes & fees
30 Aug - 31 Aug
Days Inn and Suites by Wyndham Sikeston
A hotel room with two beds, a TV, a desk, and a wardrobe.
A building with a sign that reads "The Farmstead."
A reception desk with a sign reading "The FARMSTEAD," a vending machine with snacks, and a water cooler.
A spacious lobby with a reception desk, a chandelier, and a large window.

6. The Farmstead Hotel

The Farmstead Hotel
Caruthersville
United States
Mary
€79
includes taxes & fees
31 Aug - 1 Sept
The Farmstead Hotel
A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.
A hotel patio with a gazebo, outdoor seating, and a view of the road.
An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.
An indoor swimming pool with clear water, tiled walls, and a metal ladder.

7. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
Cape Girardeau
United States
Samuel
€87
includes taxes & fees
20 Sept - 21 Sept
Candlewood Suites Cape Girardeau by IHG
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.
A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.

8. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
United States
Bonnie
€70
includes taxes & fees
31 Aug - 1 Sept
Pear Tree Inn Cape Girardeau West
A Holiday Inn Express & Suites building with a covered entrance, multiple windows, and a parking lot.
An indoor swimming pool with a tiled floor, a lifeguard chair, and a pool ladder.
A reception area with a reception desk, a large wall-mounted sign, and a potted plant.
A hotel room with a large bed, a nightstand with a lamp, a chair, and a desk with a lamp.

9. Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
Sikeston
United States
Melissa
€96
includes taxes & fees
27 Sept - 28 Sept
Holiday Inn Express & Suites Sikeston Southwest by IHG
A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.
A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.
A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.

10. Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
Sikeston
United States
Kevin
€92
includes taxes & fees
30 Aug - 31 Aug
Best Western Plus Sikeston I-55
A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.
A Hampton Inn hotel with a modern facade, a stone entrance, and a well-lit entrance area.
A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.
A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.

11. Hampton Inn Sikeston

Hampton Inn Sikeston
Sikeston
United States
Jeffrey
€103
includes taxes & fees
12 Sept - 13 Sept
Hampton Inn Sikeston
A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.

12. Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
Poplar Bluff
United States
Philip
€90
includes taxes & fees
13 Sept - 14 Sept
Hampton Inn Poplar Bluff
A modern kitchen with a central island, built-in appliances, and a view into the dining area.
A modern hotel with a stone facade, multiple windows, outdoor seating, and a visible sign for the Holiday Inn Express & Suites.
A swimming pool area with a clear pool, a lifeguard chair, and a sign indicating the pool's depth.
A hotel room with a bed, a desk, a microwave, a coffee maker, and a TV mounted on the wall.

13. Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Festus
United States
Justen
€101
includes taxes & fees
27 Sept - 28 Sept
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
A hotel room with a large bed, a nightstand, a lamp, a chair, and a mirror.
A Holiday Inn Express & Suites building with a covered entrance and multiple windows.
An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and a ceiling with recessed lighting.
A modern dining area with high tables and chairs, a television screen, and a view of the outdoors through large windows.

14. Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
Perryville
United States
Kristen
€95
includes taxes & fees
3 Sept - 4 Sept
Holiday Inn Express & Suites Perryville by IHG
An indoor swimming pool with a brick border, wooden walls, and a view of the outdoors.
A modern bathroom with a bathtub, a window with curtains, and a view of a green landscape.
A lobby with a stone fireplace, two sofas, a coffee table, and two lamps.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

15. Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection
Farmington
United States
Susan
€102
includes taxes & fees
15 Sept - 16 Sept
Crown Pointe Lodge, BW Signature Collection
A modern retail area with a display of local items and snacks.
An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.
A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

16. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
United States
Darlene
€87
includes taxes & fees
3 Sept - 4 Sept
Tru By Hilton Cape Girardeau
A hotel room with a large bathtub, a sofa, a small table, a TV, and a window with curtains.
A hotel room with a large bed, a desk with a chair, a television, and a small table with a lamp.
A spacious lobby with a checkered floor, two sofas with patterned cushions, a computer desk, and a reception area with a glass door.
A hotel lobby with two sofas, a coffee table, lamps, and a large window with a plant.

17. Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville
Perryville
United States
Elizabeth
€63
includes taxes & fees
15 Sept - 16 Sept
Super 8 by Wyndham Perryville
A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.
A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.
A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.
A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

18. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
Cape Girardeau
United States
Stephen
€60
includes taxes & fees
7 Sept - 8 Sept
Quality Inn Cape Girardeau North
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A laundry area with two washing machines and a dryer.
A breakfast area with a coffee machine, two coffee dispensers labeled 'Farm Brothers', and cereal boxes including 'Raisin Bran' and 'Frosted Flakes'.
A reception area with a wooden counter, a desk, and a computer.

19. Super 8 by Wyndham Potosi

Super 8 by Wyndham Potosi
Potosi
United States
Ross
€54
includes taxes & fees
9 Sept - 10 Sept
Super 8 by Wyndham Potosi
A modern hotel lobby with a bar area, seating, and artwork on the walls.
A swimming pool with clear blue water, surrounded by sun loungers and a lifeguard stand.
A modern hotel with a prominent sign, a covered entrance, and a well-lit exterior.
A modern kitchen with a large island, bar stools, wine bottles, and a built-in TV.

20. Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
Dexter
United States
Joyce
€94
includes taxes & fees
7 Sept - 8 Sept
Hampton Inn By Hilton Dexter
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Explore similar 3-star hotels

Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Southeast Missouri.
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3351 Percy Drive Cape Girardeau MO
€97
6 Sept - 7 Sept
includes taxes & fees
9.6/10 Exceptional! (1,003 reviews)
Drury Plaza Hotel Cape Girardeau Conference Center
Baymont by Wyndham Festus

Baymont by Wyndham Festus

1200 W. Gannon Drive Festus MO
€65
22 Sept - 23 Sept
includes taxes & fees
Baymont by Wyndham Festus
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

2608 East Malone Ave, Miner Sikeston MO
€93
14 Sept - 15 Sept
includes taxes & fees
9.6/10 Exceptional! (1,000 reviews)
Drury Inn & Suites Sikeston, MO
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Southeast Missouri

Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from Sam A. Baker State Park to K Bridge Recreation Area.

See all hotels in Southeast Missouri
A historical marker sign for the Frisco Depot, detailing its construction in 1928, architectural style, and historical significance.
Photo by Bill Dillard

Top Southeast Missouri Hotel Reviews

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent
"We stay here every time we are in Sikesons. Can't beat this hotel. Super clean 'comfortable!' beds, living room area, and bathrooms. Small hot breakfast. All for the best price out there. Don't skip on this hotel! Staff is always polite and helpful. We always love to walk out to the pond"
Cheyenna 1-night trip
Posted 7 days ago
Days Inn and Suites by Wyndham Sikeston
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

8/10 Good
"Clean and nice."
Douglass 1-night trip
Posted 10 days ago
Motel 6 Poplar Bluff, MO

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