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De Soto Hotel Guide - LGBT-Friendly Hotels in De Soto, Missouri

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Check availability on De Soto LGBT-Friendly Hotels

Our top choices for De Soto LGBT-friendly hotels

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Holiday Inn Express & Suites Farmington by IHG

Holiday Inn Express & Suites Farmington by IHG

Holiday Inn Express & Suites Farmington by IHG
2.5 star property
Farmington
8.6 out of 10, Excellent, (412)
"The staff was great!"
United States
Christopher
The price is €211
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express & Suites Farmington by IHG
Lobby
Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold
3.0 star property
Arnold
9.6 out of 10, Exceptional, (1001)
"Clean room, comfortable bed, free breakfast, dinner and drinks every night! We had a great stay, will definitely stay again!"
United States
Jacqueline
The price is €121
includes taxes & fees
21 Dec - 22 Dec
Drury Inn & Suites St. Louis Arnold
Sports facility
Hampton Inn Farmington

Hampton Inn Farmington

Hampton Inn Farmington
2.5 star property
Farmington
8.8 out of 10, Excellent, (518)
"Clean room, friendly staff."
United States
William
The price is €103
includes taxes & fees
28 Dec - 29 Dec
Hampton Inn Farmington
Lobby
Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold
2.5 star property
Arnold
9.4 out of 10, Exceptional, (1002)
"The staff was very friendly and the rooms were very nice and clean"
United States
Connie
The price is €89
includes taxes & fees
21 Dec - 22 Dec
Pear Tree Inn St. Louis Arnold
Exterior
WoodSpring Suites St. Louis Arnold

WoodSpring Suites St. Louis Arnold

WoodSpring Suites St. Louis Arnold
2.5 star property
Arnold
6.0 out of 10, (440)
"Location was great as was staff"
United States
Randall
The price is €80
includes taxes & fees
25 Dec - 26 Dec
WoodSpring Suites St. Louis Arnold
Free buffet breakfast
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
2.5 star property
Festus
9.4 out of 10, Exceptional, (700)
"Clean, spotless, great room, front desk staff was excellent! Parking great!"
United States
Rick
The price is €132
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top De Soto Hotel Reviews

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Frequently asked questions

Searching for LGBTQ-friendly accommodation in De Soto?
Consider this your open invitation to pack your bags and find LGBTQ-friendly hotels in De Soto on our website. Discover the people, places and traditions found only in De Soto.
What should I do while I'm visiting De Soto?
During your trip, get out and enjoy everything De Soto has to offer. You and your travelling companions may want to visit Sunrise Lake Beach, Washington State Park and Big River. While you're here, create some great memories of your trip with stops at Big Lake, Redfield's Flea Market and Railroad Workers Memorial Park.
What is a gay-friendly hotel in De Soto?
LGBTQ-friendly hotels, also known as gay-friendly hotels, welcome all travellers who identify as LGBTQIA+. Expedia has worked with the International Gay and Lesbian Travel Association (IGLTA) to compile a selection of LGBTQ-friendly hotels worldwide. In De Soto, hotels affiliated with IGLTA will provide lesbian, gay, bisexual and transgender adventurers with the information needed to design the trip of a lifetime.
What can I expect from LGBTQ-friendly accommodation in De Soto?
Stay at a gay-friendly hotel in De Soto and you'll be around like-minded people, so you can relax and enjoy your trip. Some of Expedia's LGBTQ-friendly hotels go the extra mile and offer wedding ceremonies and honeymoon packages for same-sex couples.