Downtown San Francisco Hotel Guide - Business Hotels in Downtown San Francisco, San Francisco

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Check availability on Downtown San Francisco Business Hotels

Top Downtown San Francisco Business Hotels

Grand Bay Hotel San Francisco
Enjoy al fresco dining amidst a serene poolside setting, surrounded by stylish tables and chairs.

Grand Bay Hotel San Francisco

4.0 star property
8.2 out of 10, Very good, (1000)
"Awesome property not far from many stores and resturaunts."
The price is €140
includes taxes & fees
22 Aug - 23 Aug
Grand Bay Hotel San Francisco
Hyatt Regency San Francisco Airport
Experience the grandeur of this hotel, featuring a stunning glass atrium and beautifully manicured grounds.

Hyatt Regency San Francisco Airport

4.0 star property
8.8 out of 10, Excellent, (1292)
"great stay"
The price is €146
includes taxes & fees
23 Aug - 24 Aug
Hyatt Regency San Francisco Airport
Hotel Riu Plaza Fisherman's Wharf
Relax in our spacious lobby with sofas, armchairs, and a dining area.

Hotel Riu Plaza Fisherman's Wharf

4.0 star property
9.0 out of 10, Wonderful, (6636)
"Great stay "
The price is €174
includes taxes & fees
26 Aug - 27 Aug
Hotel Riu Plaza Fisherman's Wharf
Hilton San Francisco Union Square
Experience the unique architecture of this high-rise hotel, featuring a distinctive rounded corner and a prominent dome.

Hilton San Francisco Union Square

4.0 star property
8.2 out of 10, Very good, (1067)
"Well located hotel to spend the night!"
The price is €159
includes taxes & fees
28 Aug - 29 Aug
Hilton San Francisco Union Square
Hyatt Regency San Francisco Downtown SOMA
Hyatt Regency San Francisco Downtown Soma features a modern architectural design with a flat roof and large windows.

Hyatt Regency San Francisco Downtown SOMA

4.0 star property
9.4 out of 10, Exceptional, (1319)
"Great staff and great room."
The price is €192
includes taxes & fees
22 Aug - 23 Aug
Hyatt Regency San Francisco Downtown SOMA
Hotel VIA
Relax in style with comfortable seating and expansive views of the surrounding area.

Hotel VIA

4.0 star property
9.2 out of 10, Wonderful, (1362)
"Great stay!"
The price is €179
includes taxes & fees
1 Sept - 2 Sept
Hotel VIA
Hyatt Regency San Francisco
Experience the sleek, modern design of this hotel, featuring a prominent glass facade and illuminated windows.

Hyatt Regency San Francisco

4.0 star property
9.2 out of 10, Wonderful, (1786)
"Beautiful hotel!"
The price is €203
includes taxes & fees
28 Aug - 29 Aug
Hyatt Regency San Francisco
Omni San Francisco Hotel
Step into the grand lobby, featuring a spacious floor with intricate patterns, a grand staircase, and a reception desk.

Omni San Francisco Hotel

4.5 star property
9.6 out of 10, Exceptional, (1149)
"Great room, location and staff were excellent!"
The price is €204
includes taxes & fees
29 Aug - 30 Aug
Omni San Francisco Hotel
The Westin St. Francis San Francisco on Union Square
Enjoy panoramic city views from large windows in this elegantly designed room with high ceilings and a chandelier.

The Westin St. Francis San Francisco on Union Square

4.5 star property
8.8 out of 10, Excellent, (2512)
"This is absolutely the best hotel "
The price is €206
includes taxes & fees
6 Sept - 7 Sept
The Westin St. Francis San Francisco on Union Square
Hilton San Francisco Financial District
Experience the vibrant city from the doorstep of this urban hotel, with stunning views of the surrounding high-rise buildings.

Hilton San Francisco Financial District

4.0 star property
8.6 out of 10, Excellent, (1604)
"Great location and awesome staff "
The price is €122
includes taxes & fees
24 Aug - 25 Aug
Hilton San Francisco Financial District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Downtown San Francisco Hotel Reviews

Handlery Union Square Hotel

Handlery Union Square Hotel

10/10 Excellent
"Nice place to stay in SF. "
Scott 4-night trip
Posted 8 hours ago
Handlery Union Square Hotel

Frequently asked questions

Why book your business-friendly hotel in Downtown San Francisco with Expedia?
At Expedia, our top task is to help you locate an excellent stay at the right price. From luxurious, corporate-friendly escapes to affordable hotels filled with conveniences, you'll have your next work trip arranged in a couple of clicks.
How can I find cheap business-friendly hotels in Downtown San Francisco?
When work takes you to Downtown San Francisco, our "business friendly" filter will help you find the perfect hotel. From fast WiFi to conference spaces and in-room desks, they have the amenities you need to do your job. You can also refine your search by your preferred star rating and budget to view the most affordable stays.