Downtown San Francisco Hotel Guide - Business Hotels in Downtown San Francisco, San Francisco

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Downtown San Francisco Business Hotels

Tonight
31 Jul - 1 Aug
Tomorrow
1 Aug - 2 Aug
This weekend
1 Aug - 3 Aug
Next weekend
8 Aug - 10 Aug

Top Downtown San Francisco Business Hotels

Parc 55 San Francisco - A Hilton Hotel
Lobby

Parc 55 San Francisco - A Hilton Hotel

4.0 star property
8.6 out of 10, Excellent, (1391)
"Great area"
The price is €148
includes taxes & fees
28 Aug - 29 Aug
Parc 55 San Francisco - A Hilton Hotel
Hotel VIA
Sun deck

Hotel VIA

4.0 star property
9.2 out of 10, Wonderful, (1350)
"Great stay!"
The price is €166
includes taxes & fees
22 Aug - 23 Aug
Hotel VIA
Hyatt Regency San Francisco
Exterior

Hyatt Regency San Francisco

4.0 star property
9.2 out of 10, Wonderful, (1777)
"Really nice hotel with a great location. "
The price is €207
includes taxes & fees
28 Aug - 29 Aug
Hyatt Regency San Francisco
San Francisco Marriott Marquis
2 restaurants, breakfast, dinner served; Californian cuisine

San Francisco Marriott Marquis

4.0 star property
8.8 out of 10, Excellent, (1269)
"Great stay!"
The price is €206
includes taxes & fees
14 Aug - 15 Aug
San Francisco Marriott Marquis
Hyatt Regency San Francisco Downtown SOMA
Exterior

Hyatt Regency San Francisco Downtown SOMA

4.0 star property
9.2 out of 10, Wonderful, (1339)
"Great staff and great room."
The price is €187
includes taxes & fees
22 Aug - 23 Aug
Hyatt Regency San Francisco Downtown SOMA
Hilton San Francisco Financial District
Front of property – evening/night

Hilton San Francisco Financial District

4.0 star property
8.6 out of 10, Excellent, (1568)
"Great spot for a vacation’ "
The price is €131
includes taxes & fees
24 Aug - 25 Aug
Hilton San Francisco Financial District
W San Francisco
Exterior

W San Francisco

4.5 star property
9.0 out of 10, Wonderful, (1004)
"The most comfortable beds I’ve slept in! All staff were very helpful. Great stay!"
The price is €186
includes taxes & fees
22 Aug - 23 Aug
W San Francisco
BEI San Francisco, Trademark Collection by Wyndham
Meeting facility

BEI San Francisco, Trademark Collection by Wyndham

4.0 star property
7.0 out of 10, Good, (1059)
"Great location near Bill Graham"
The price is €143
includes taxes & fees
10 Aug - 11 Aug
BEI San Francisco, Trademark Collection by Wyndham
Club Quarters Hotel in San Francisco
Terrace/patio

Club Quarters Hotel in San Francisco

4.0 star property
8.8 out of 10, Excellent, (2478)
"The location..price..and comfortable room make it a great stay."
The price is €176
includes taxes & fees
7 Aug - 8 Aug
Club Quarters Hotel in San Francisco
Hilton San Francisco Union Square
Exterior detail

Hilton San Francisco Union Square

4.0 star property
8.2 out of 10, Very good, (1059)
"Well located hotel to spend the night!"
The price is €163
includes taxes & fees
28 Aug - 29 Aug
Hilton San Francisco Union Square
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Downtown San Francisco Hotel Reviews

Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

10/10 Excellent
"Excellent hotel. Excellent location in the heart of San Francisco downtown "
JOAQUIN 1-night trip
Posted 14 hours ago
Chancellor Hotel on Union Square

Frequently asked questions

Why book your business-friendly hotel in Downtown San Francisco with Expedia?
At Expedia, our top task is to help you locate an excellent stay at the right price. From luxurious, corporate-friendly escapes to affordable hotels filled with conveniences, you'll have your next work trip arranged in a couple of clicks.
How can I find cheap business-friendly hotels in Downtown San Francisco?
When work takes you to Downtown San Francisco, our "business friendly" filter will help you find the perfect hotel. From fast WiFi to conference spaces and in-room desks, they have the amenities you need to do your job. You can also refine your search by your preferred star rating and budget to view the most affordable stays.