Downtown San Francisco Hotel Guide - Business Hotels in Downtown San Francisco, San Francisco

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Check availability on Downtown San Francisco Business Hotels

Tonight
8 Oct - 9 Oct
Tomorrow
9 Oct - 10 Oct
This weekend
10 Oct - 12 Oct
Next weekend
17 Oct - 19 Oct

Top Downtown San Francisco Business Hotels

InterContinental San Francisco by IHG
Exterior

InterContinental San Francisco by IHG

4.0 star property
9.0 out of 10, Wonderful, (1016)
"Great location, friendly staff and comfy beds!"
The price is €194
includes taxes & fees
31 Oct - 1 Nov
InterContinental San Francisco by IHG
Hilton San Francisco Union Square
Exterior detail

Hilton San Francisco Union Square

4.0 star property
8.2 out of 10, Very good, (1098)
"Hotel was amazing "
The price is €175
includes taxes & fees
17 Oct - 18 Oct
Hilton San Francisco Union Square
Hotel VIA
Sun deck

Hotel VIA

4.0 star property
9.2 out of 10, Wonderful, (1445)
"Great stay"
The price is €208
includes taxes & fees
7 Nov - 8 Nov
Hotel VIA
Hyatt Regency San Francisco
Exterior

Hyatt Regency San Francisco

4.0 star property
9.2 out of 10, Wonderful, (1926)
"Really enjoyed our stay at this beautiful hotel."
The price is €232
includes taxes & fees
10 Oct - 11 Oct
Hyatt Regency San Francisco
Holiday Inn Golden Gateway by IHG
Outdoor pool, open 9:00 AM to 7:00 PM, pool loungers

Holiday Inn Golden Gateway by IHG

3.5 star property
9.0 out of 10, Wonderful, (4670)
"Had a great stay !"
The price is €113
includes taxes & fees
2 Nov - 3 Nov
Holiday Inn Golden Gateway by IHG
W San Francisco
Exterior

W San Francisco

4.5 star property
9.0 out of 10, Wonderful, (1006)
"I had a great stay. Very quiet and friendly staff. Will definitely stay again."
The price is €183
includes taxes & fees
1 Nov - 2 Nov
W San Francisco
Marines Memorial Club & Hotel
Indoor pool

Marines Memorial Club & Hotel

3.0 star property
10.0 out of 10, Exceptional, (2)
"The place is incredible. Every floor was like being in a museum of amazing Marine Corps history. I will definitely be back. Semper Fi! "
Marines Memorial Club & Hotel
Omni San Francisco Hotel
Lobby

Omni San Francisco Hotel

4.5 star property
9.6 out of 10, Exceptional, (1195)
"Great hotel"
The price is €191
includes taxes & fees
31 Oct - 1 Nov
Omni San Francisco Hotel
Grand Hyatt San Francisco
Restaurant

Grand Hyatt San Francisco

4.0 star property
8.8 out of 10, Excellent, (1005)
"Very nice hotel with great location!"
The price is €194
includes taxes & fees
31 Oct - 1 Nov
Grand Hyatt San Francisco
Hyatt Regency San Francisco Downtown SOMA
Exterior

Hyatt Regency San Francisco Downtown SOMA

4.0 star property
9.4 out of 10, Exceptional, (1293)
"Great stay"
The price is €193
includes taxes & fees
30 Oct - 31 Oct
Hyatt Regency San Francisco Downtown SOMA
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Downtown San Francisco Hotel Reviews

Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

10/10 Excellent
"Awesome experience! Great staff, excellent location and retro rooms. We’ve already booked our next stay."
mike 1-night trip
Posted 2 days ago
Chancellor Hotel on Union Square

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Explore a world of travel with Expedia

Frequently asked questions

Why book your business-friendly hotel in Downtown San Francisco with Expedia?
At Expedia, our top task is to help you locate an excellent stay at the right price. From luxurious, corporate-friendly escapes to affordable hotels filled with conveniences, you'll have your next work trip arranged in a couple of clicks.
How can I find cheap business-friendly hotels in Downtown San Francisco?
When work takes you to Downtown San Francisco, our "business friendly" filter will help you find the perfect hotel. From fast WiFi to conference spaces and in-room desks, they have the amenities you need to do your job. You can also refine your search by your preferred star rating and budget to view the most affordable stays.