El Santuario Hotels

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for El Santuario hotels

MONTANA ECO HOTEL

MONTANA ECO HOTEL
2.0 star property
El Santuario
  • cleanliness
    Sustainable farm stay near El Santuario offers eco-friendly accommodation with mountain views.
The price is €121
15 Feb - 16 Feb
MONTANA ECO HOTEL

Hotel Bossanova

Hotel Bossanova
3.0 star property
Rionegro
9.4 out of 10, Exceptional, (6 reviews)
"Great staff. Location. "
United States
Pedro
The price is €28
1 Mar - 2 Mar
Hotel Bossanova

Hotel Zona A

Hotel Zona A
3.0 star property
El Poblado
9.0 out of 10, Wonderful, (188 reviews)
"The staff very friendly!! Everything clean. It was so close to everything I felt very safe. Excellent service "
United States
Marcia
Hotel Zona A

The Host Medellin Only Adults

The Host Medellin Only Adults
3.0 star property
El Poblado
9.6 out of 10, Exceptional, (31 reviews)
  • cleanliness
    Sophisticated adults-only retreat in Medellín, steps from vibrant Poblado Park.
"Great ambience and room, excellent breakfast "
United States
Shailendra
The price is €139
21 Feb - 22 Feb
The Host Medellin Only Adults

LIN Boutique Hotel by HOUSY HOST

LIN Boutique Hotel by HOUSY HOST
3.0 star property
El Poblado
9.0 out of 10, Wonderful, (159 reviews)
  • cleanliness
    Experience a boutique retreat steps from vibrant Lleras Park in Medellín.
"Very clean room, very good staff, excellent breakfast and the cleaning staff amazing. I’m very please with her job and honesty ,"
United States
Carlos M
The price is €67
15 Feb - 16 Feb
LIN Boutique Hotel by HOUSY HOST

Hotel Helene

Hotel Helene
3.5 star property
El Poblado
8.4 out of 10, Very good, (202 reviews)
  • cleanliness
    Stay a 5-minute walk from Lleras Park in a prime Medellín location.
"The staff was incredible. The bathroom in the room was kind of small but the staff more than made up for it with their friendly service."
United States
Sandra
The price is €40
12 Mar - 13 Mar
Hotel Helene

23 Living

23 Living
3.0 star property
El Poblado
9.6 out of 10, Exceptional, (24 reviews)
  • cleanliness
    Stylish Medellín hotel with rooftop bars steps from vibrant Lleras Park.
"Loved this property. Architecture is gorgeous. Beautiful design features in the rooms. Location could not be better. Excellent service from the staff! "
United States
Christopher
The price is €103
9 Mar - 10 Mar
23 Living

MG Hotels & Suites

MG Hotels & Suites
3.5 star property
Rionegro
8.8 out of 10, Excellent, (215 reviews)
  • cleanliness
    Take in the sun at Rionegro's sauna-equipped haven, steps from popular malls.
"The room was spotless, my family felt very safe. The front office staff was very accommodating, friendly and helpful with directions to the nearest mall. I would have given it 5 stars but the pool was being worked on and my granddaughters wanted to swim. Other than that, everything was well kept."
United States
Xochitl
The price is €122
2 Mar - 3 Mar
MG Hotels & Suites

La Quinta by Wyndham Medellin

La Quinta by Wyndham Medellin
3.5 star property
San Diego
8.8 out of 10, Excellent, (1,001 reviews)
  • cleanliness
    Unwind in Medellín with poolside refreshments and convenient city access.
"Excellent room, very clean and friendly staff "
United States
Anelsy
The price is €66
27 Feb - 28 Feb
La Quinta by Wyndham Medellin

Casa Rosé Hotel

Casa Rosé Hotel
3.5 star property
El Carmen de Viboral
9.6 out of 10, Exceptional, (58 reviews)
  • cleanliness
    Tranquil retreat in El Carmen de Viboral with deep-tissue massages and dining.
"Friendly staff, clean room, excellent location."
United States
Daniel
The price is €66
16 Feb - 17 Feb
Casa Rosé Hotel

Alfahar Hotel

Alfahar Hotel
3.0 star property
El Carmen de Viboral
9.8 out of 10, Exceptional, (21 reviews)
  • cleanliness
    Serene retreat in El Carmen de Viboral with complimentary daily breakfast.
"great hotel, good staff "
United States
matania
Alfahar Hotel

La Campana Hotel Boutique

La Campana Hotel Boutique
3.0 star property
El Poblado
9.0 out of 10, Wonderful, (216 reviews)
  • cleanliness
    Colonial retreat near Poblado and Lleras Park, perfect for exploring Medellín.
"Our room was a great space to unwind and relax - large and comfortable. The staff was excellent - very helpful and accommodating. It’s a beautiful hotel and walkable to restaurants."
United States
Elisabeth
La Campana Hotel Boutique

Hotel Madeiro

Hotel Madeiro
3.0 star property
El Poblado
8.4 out of 10, Very good, (252 reviews)
  • cleanliness
    Unwind at a spa sanctuary near vibrant Lleras Park in Medellín's El Poblado district.
"Incredible location and my time at Madeiro was very nice. I recommend everyone to stay here. "
United States
David
Hotel Madeiro

Nomada Hotel Origen

Nomada Hotel Origen
3.0 star property
El Poblado
9.4 out of 10, Exceptional, (114 reviews)
  • cleanliness
    Enjoy the hip El Poblado area with cafes, parks, and vibrant nightlife.
"Staff was AMAZING "
United States
Yoselin
The price is €63
15 Feb - 16 Feb
Nomada Hotel Origen

Hotel Dorado san luis

Hotel Dorado san luis
2.0 star property
San Luis
2.0 out of 10, (1 review)
The price is €25
20 Feb - 21 Feb
Hotel Dorado san luis

The Somos Central Hotel Poblado

The Somos Central Hotel Poblado
4.0 star property
El Poblado
9.0 out of 10, Wonderful, (269 reviews)
  • cleanliness
    Explore this hip hotel just steps from parks in Medellín's vibrant El Poblado district.
"The staff was wonderful and the location was great"
United States
Eve
The price is €63
17 Feb - 18 Feb
The Somos Central Hotel Poblado

Sites Hotel

Sites Hotel
4.0 star property
El Poblado
9.2 out of 10, Wonderful, (1,129 reviews)
  • cleanliness
    Stay in a modern, fully-equipped apartment near Medellín's Poblado area.
"Clean room, wonderful staff and great location!!!"
United States
Marleny
The price is €92
16 Feb - 17 Feb
Sites Hotel

Hampton by Hilton Medellin

Hampton by Hilton Medellin
3.5 star property
El Poblado
8.8 out of 10, Excellent, (505 reviews)
"Exellent food and Staff"
United States
Armando
The price is €86
27 Feb - 28 Feb
Hampton by Hilton Medellin

HOTEL BAMBU MILLA DE ORO

HOTEL BAMBU MILLA DE ORO
2.5 star property
El Poblado
8.6 out of 10, Excellent, (182 reviews)
  • cleanliness
    Step into modern comfort minutes from Santafé Mall and Poblado's buzz.
"Clean room, nice staff and nice location"
United States
Valeska
The price is €61
22 Feb - 23 Feb
HOTEL BAMBU MILLA DE ORO

Hotel Poblado Alejandria

Hotel Poblado Alejandria
3.5 star property
El Poblado
9.0 out of 10, Wonderful, (491 reviews)
  • cleanliness
    Rooftop views await in El Poblado, steps from premier shopping centers.
"Friendly staff, excellent breakfast and clean room "
United States
Betty
The price is €71
27 Feb - 28 Feb
Hotel Poblado Alejandria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Learn more about El Santuario

Check out San Nicolás Mall and Rock of Guatapé—just a couple of the sights around El Santuario.

El Santuario, Antioquia, Colombia. June 28, 2025. Panoramic drone view of the town's main church.

Top El Santuario Hotel Reviews

More cheap stays in El Santuario

Frequently asked questions

Where is the best place to stay in El Santuario?
Located 21.6 mi (34.7 km) from the heart of El Santuario, Calle Flora Hotel by Jalo is a top choice for your stay, based on our traveller data. Two other choices for your visit to the area are Heiss Hotel By Jalo and Hashtag 98 Hotel By Jalo. See all available top hotels, or vacation rentals in El Santuario.
What are some of the best holiday rentals that El Santuario has to offer?
EP Casa Uribe Architecture Art & Nature: This holiday home rental outside of El Santuario is located in a shopping district, and has an outdoor pool, a balcony and laundry facilities to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge and a stovetop. See all vacation rentals in El Santuario.
If I need to cancel my hotel reservation in El Santuario, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in El Santuario.
How is it to stay in El Santuario?
Visitors will definitely enjoy all that El Santuario has to offer. In El Santuario, there are 2 hotels and other accommodation options to choose from. Find out more about El Santuario.
What are the top places to visit in El Santuario?
Places to visit in the wider area include San Nicolás Mall, Rock of Guatapé and Parque Comfama. You'll also find Piedra del Marial and Llanogrande Mall in the area. Take a look at what more there is to see and do in Expedia's El Santuario guide.
What's the seasonal weather like in El Santuario?
The hottest months are usually August and September, with an average temperature of 17°C, while the coldest months are January and July, with an average of 17°C. The rainiest months in El Santuario are April, May, October and November, with each month seeing an average of 439 mm of rainfall.

Explore a world of travel with Expedia