Santo Spirito

Florence

A grand church interior with high vaulted ceilings, large columns, and a central altar.
A stone bridge over a calm river, with historic buildings on either side.
A bustling outdoor market with white tents and various stalls.
A church with a bell tower, a circular window, and a weather vane.
A cityscape with a river, a bridge, and mountains in the background.

Stay near popular Santo Spirito attractions

A town square with historic buildings, a church, and a bell tower.

Piazza Santo Spirito

9.6/10 (8 reviews)
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and notable monuments in this vibrant area.
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Things to do

Florence: San Gimignano, Siena, Monteriggioni, Chianti & Lunch with Wine

Florence: San Gimignano, Siena, Monteriggioni, Chianti & Lunch with Wine

€79
per adult
88% of travellers recommend
Florence: San Gimignano, Siena, Monteriggioni, Chianti & Lunch with Wine
Michaelangelo's David

Accademia timed-entry Ticket with Instant Delivery & Priority Access

€41
per adult
94% of travellers recommend
Accademia timed-entry Ticket with Instant Delivery & Priority Access
Skip-the-Line Duomo: Priority-Access 30-Minute Guided Tour

Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour

€20
per adult
80% of travellers recommend
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
Tuscany in 1 day: Pisa, San Gimignano and Siena with Lunch

Tuscany in 1 day from Florence: Pisa, San Gimignano & Siena with Lunch

€49
per adult
78% of travellers recommend
Tuscany in 1 day from Florence: Pisa, San Gimignano & Siena with Lunch
People riding scooters in Tuscany

Florence Vespa Tour: Tuscan Hills, Food and Chianti Wine

€111
per adult
100% of travellers recommend
Florence Vespa Tour: Tuscan Hills, Food and Chianti Wine
City Sightseeing Florence Hop-on Hop-off

City Sightseeing Florence Hop-on Hop-off Bus Tour

€29
per adult
76% of travellers recommend
City Sightseeing Florence Hop-on Hop-off Bus Tour
See all activities in Florence

Top hotels in Santo Spirito

Hotel Horto Convento

Hotel Horto Convento

4 out of 5
Viale Ariosto, 13 Florence FI
The price is €180 per night from 29 Jul to 30 Jul
€180
29 Jul - 30 Jul
includes taxes & fees
Stay at this hotel in Florence. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff in their reviews. Popular ...
9.8/10 Exceptional! (687 reviews)
"Beautiful, clean, amazing breakfast, really nice staff. 10/10 recommendation"

Reviewed on 7 Jul 2026

Hotel Horto Convento
La Torre Del Cestello

La Torre Del Cestello

Via Borgo San Frediano, 8 Florence FI
The price is €131 per night from 4 Aug to 5 Aug
€131
4 Aug - 5 Aug
includes taxes & fees
Stay at this residence in Florence. Enjoy free Wi-Fi, valet parking (surcharge) and daily housekeeping. Popular attractions Ponte Vecchio and Piazza della Signoria ...
9.2/10 Wonderful! (277 reviews)
"We had a wonderful stay at Torre del Castello. The location is perfect, making it easy to enjoy the surrounding area while still having a comfortable and peaceful place to return to. The property was exactly as described, clean, spacious, and very well maintained. The accommodations were comfortable, ..."

Reviewed on 14 Jul 2026

La Torre Del Cestello
UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze

4 out of 5
Via Pisana 59 Florence FI
The price is €103 per night from 26 Jul to 27 Jul
€103
26 Jul - 27 Jul
includes taxes & fees
Stay at this boutique hotel in Florence. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff in their reviews. Popular ...
8.4/10 Very good! (1,003 reviews)
"Great staff and well located especially for the West Bank of the city. Slightly too far out for the city etc"

Reviewed on 12 May 2026

UNA Hotels Vittoria Firenze
Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie

Via dei Serragli 49 Florence FI
The price is €84 per night from 4 Aug to 5 Aug
€84
4 Aug - 5 Aug
includes taxes & fees
Stay at this guesthouse in Florence. Enjoy free Wi-Fi, 2 meeting rooms and satellite TV channels. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (230 reviews)
"I had a lovely stay! Staff were helpful"

Reviewed on 13 Jul 2026

Foresteria Valdese di Firenze - Casa per Ferie
Palazzo Mannaioni Suites

Palazzo Mannaioni Suites

4 out of 5
Via Maffia 9 - 17r Florence FI
The price is €190 per night from 19 Jul to 20 Jul
€190
19 Jul - 20 Jul
includes taxes & fees
Stay at this residence in Florence. Enjoy free Wi-Fi, concierge services and premium bedding. Our guests praise the helpful staff in their reviews. Popular attractions ...
9.2/10 Wonderful! (1,138 reviews)
"The staff was very helpful. We got the recommendation on good local restaurants which were all excellent."

Reviewed on 15 Jul 2026

Palazzo Mannaioni Suites
Torre di Bellosguardo

Torre di Bellosguardo

4 out of 5
Via Roti Michelozzi 2 Florence FI
The price is €551 per night from 17 Jul to 18 Jul
€551
17 Jul - 18 Jul
includes taxes & fees
Stay at this business-friendly hotel in Florence. Enjoy free Wi-Fi, free parking and an outdoor pool. Popular attractions Ponte Vecchio and Uffizi Gallery are ...
9/10 Wonderful! (103 reviews)
"This was by far the best hotel I have ever stayed at, as someone who travels solo often sometimes you are just looking for some peace and not having to do everything on your own. I am in awe of the property. If you are looking for privacy, story book views, and gardens this is the place to be. The ..."

Reviewed on 29 Oct 2025

Torre di Bellosguardo
See all 521 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Spirito

Find the best Santo Spirito areas for the activities you enjoy most. Learn more about Santo Spirito
Learn more about Santo Spirito
A river with buildings on the right bank.

Historic Centre of Florence

Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Piazza della Signoria are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

A historic building with intricate architectural details, including a dome and ornate facades.

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Piazza del Duomo while you're exploring the neighbourhood.

A historic bridge with arches over a river, surrounded by yellow buildings and a crowd of people.

San Giovanni

If you're spending some time in San Giovanni, Piazza della Signoria and Uffizi Gallery are top sights worth seeing.

A historic church with intricate architecture and a large open plaza with people.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

An ornate building with intricate architectural details and a clear blue sky in the background.

Santa Croce

Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Santo Spirito

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