Santo Spirito

Florence

Province of Florence showing interior views, heritage elements and a church or cathedral
Province of Florence showing interior views, heritage elements and a church or cathedral
Province of Florence which includes a bridge, night scenes and a river or creek
Province of Florence featuring markets and street scenes
Province of Florence featuring heritage architecture and a church or cathedral

Top hotels in Santo Spirito

Hotel Horto Convento

Hotel Horto Convento

4 out of 5
Viale Ariosto, 13 Florence FI
The price is €129 per night from 8 Mar to 9 Mar
€129
8 Mar - 9 Mar
includes taxes & fees
Stay at this hotel in Florence. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff in their reviews. Popular ...
9.8/10 Exceptional! (622 reviews)
Horto Convento was a wonderful place to stay. Our room was immaculate and breakfast was terrific. The staff, especially Stefano and Elena were very helpful with directions and suggestions. We truly wished we could have stayed there more than our one night.

Reviewed on 25 Feb 2026

Hotel Horto Convento
Palazzo Mannaioni Suites

Palazzo Mannaioni Suites

4 out of 5
Via Maffia 9 - 17r Florence FI
Stay at this residence in Florence. Enjoy free Wi-Fi, concierge services and satellite TV channels. Our guests praise the helpful staff in their reviews. Popular ...
9.2/10 Wonderful! (1,088 reviews)
Beautiful room, very thorough check in with a very nice man who gave us great dining recommendations. We loved having a big fridge. The shower was a bit small but overall we really enjoyed the room.

Reviewed on 26 Feb 2026

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Palazzo Mannaioni Suites
UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze

4 out of 5
Via Pisana 59 Florence FI
The price is €128 per night from 8 Mar to 9 Mar
€128
8 Mar - 9 Mar
includes taxes & fees
Stay at this boutique hotel in Florence. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff in their reviews. Popular ...
8.4/10 Very Good! (1,000 reviews)
Perfect stay! Not only was the check-in smooth, but everything else was also satisfying. The breakfast was delicious, the staff were friendly, and the location was ideal. There wasn't a single thing I didn't like. I’ll definitely be back!

Reviewed on 1 Jan 2026

UNA Hotels Vittoria Firenze
La Torre Del Cestello

La Torre Del Cestello

Via Borgo San Frediano, 8 Florence FI
Stay at this residence in Florence. Enjoy free Wi-Fi, valet parking (surcharge) and daily housekeeping. Popular attractions Pitti Palace and Ponte Vecchio are ...
9/10 Wonderful! (238 reviews)
Personal je velmi pratelsky, neni co vytknout. Ubytovani je v super lokalite, kousek od hlavnich památek . Postel velmi pohodlna, koupelna prostorna .

Reviewed on 25 Feb 2026

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La Torre Del Cestello
Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie

Via dei Serragli 49 Florence FI
Stay at this property in Florence. Enjoy free Wi-Fi, 2 meeting rooms and satellite TV channels. Our guests praise the helpful staff and the clean rooms in their ...
8.8/10 Excellent! (197 reviews)
Room was very dated, old and cold. Shower seemed particularly dirty and the water was cold. Of the 9 hotels we have stayed in on our travels thus far this was the only 3 star that on this site rated 4.4. Good location. Lovely staff. Wouldn’t stay again.

Reviewed on 2 Jan 2026

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Foresteria Valdese di Firenze - Casa per Ferie
Casa Santo Nome di Gesù

Casa Santo Nome di Gesù

Piazza del Carmine, 21 Florence FI
Stay at this guesthouse in Florence. Enjoy free breakfast, free Wi-Fi and parking (surcharge). Our guests praise the helpful staff in their reviews. Popular ...
8.8/10 Excellent! (344 reviews)
Pretty neat place. Run by nuns. Great building. Friendly staff Breakfast included. Rooms simple clean. Beautiful location. Would definitely go back.

Reviewed on 28 Jan 2026

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Casa Santo Nome di Gesù
See all 493 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Santo Spirito

Brancacci Chapel which includes a church or cathedral and heritage architecture

San Frediano

San Frediano is known for its stunning river views, and you can plan a trip to Piazza Santo Spirito and Boboli Gardens while you're in town.

San Frediano
Arcetri which includes a river or creek, a sunset and a bridge

Oltrarno

4.5/5(165 area reviews)

Oltrarno is a destination visitors seek out for its fascinating museums, picturesque gardens and beautiful river views. You might also want to check out attractions like Pitti Palace or Via Maggio while you're exploring the neighbourhood.

Oltrarno
Santa Maria Novella which includes heritage architecture, a church or cathedral and street scenes

Santa Maria Novella

4/5(254 area reviews)

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Santa Maria Novella
Ponte Vecchio showing a bridge and a river or creek

San Giovanni

If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

San Giovanni
Arcetri showing a bridge and a river or creek

Historic Centre of Florence

Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Piazza di Santa Maria Novella and Via de' Calzaiuoli are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

Historic Centre of Florence
Duomo featuring heritage architecture and street scenes as well as a small group of people

Duomo

4.5/5(418 area reviews)

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Piazza di Santa Maria Novella or Via de' Calzaiuoli while you're exploring the neighbourhood.

Duomo

Santo Spirito

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