Florence Hotel Guide. Hotels in Santo Spirito, Florence, Italy

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santo Spirito hotels

Mamo Florence - Bice & Krizia Apartments

Mamo Florence - Bice & Krizia Apartments
Santo Spirito
9.4 out of 10, Exceptional, (3 reviews)
"Very nice apartment and great location. The included parking and laundry facilities were the reason we selected the property, and were very happy with everything. Overall a lovely stay. "
United States
Michele
The price is €217
includes taxes & fees
22 Apr - 23 Apr
Mamo Florence - Bice & Krizia Apartments

Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie
Santo Spirito
8.8 out of 10, Excellent, (202 reviews)
"The room was clean a d comfortable, and the staff was very courteous and helpful. The location was also good with most attractions being a 30 to 40 minute walk or less."
United States
Roger
The price is €117
includes taxes & fees
19 Apr - 20 Apr
Foresteria Valdese di Firenze - Casa per Ferie

La Fonderia Firenze

La Fonderia Firenze
Santo Spirito
9.6 out of 10, Exceptional, (177 reviews)
"The room was beautiful and clean, the staff was pleasant, breakfast was fantastic, 10/10"
United States
Dan
The price is €144
includes taxes & fees
27 Apr - 28 Apr
La Fonderia Firenze

1900 Artevita

1900 Artevita
Santo Spirito
8.8 out of 10, Excellent, (180 reviews)
"Great old world charm. Felt like I was living in an apartment Not corporate style place but a real Italian experience. "
United States
Drew
The price is €146
includes taxes & fees
24 Apr - 25 Apr
1900 Artevita

Residenza D'Epoca Al Numero 8

Residenza D'Epoca Al Numero 8
Santo Spirito
9.0 out of 10, Wonderful, (149 reviews)
"Excellent location and very friendly staff."
Canada
Scott
The price is €173
includes taxes & fees
19 Apr - 20 Apr
Residenza D'Epoca Al Numero 8

La Torre Del Cestello

La Torre Del Cestello
Santo Spirito
9.2 out of 10, Wonderful, (248 reviews)
"It was in a great location, we had an excellent view from our room."
United States
Tonya
The price is €173
includes taxes & fees
19 Apr - 20 Apr
La Torre Del Cestello

L'Antica Porta Boutique B&B

L'Antica Porta Boutique B&B
Santo Spirito
9.0 out of 10, Wonderful, (22 reviews)
"Very goord place to stay"
United States
Victor
The price is €123
includes taxes & fees
20 Apr - 21 Apr
L'Antica Porta Boutique B&B

Ottantotto Firenze

Ottantotto Firenze
Santo Spirito
9.6 out of 10, Exceptional, (170 reviews)
"Great location and extremely charming!"
United States
Brook
The price is €427
includes taxes & fees
14 May - 15 May
Ottantotto Firenze

AdAstra Suites

AdAstra Suites
Santo Spirito
9.8 out of 10, Exceptional, (226 reviews)
"Gorgeous room in a beautiful property, very helpful staff, tranquil setting"
United Kingdom
Olivia
The price is €409
includes taxes & fees
19 Apr - 20 Apr
AdAstra Suites

Torre di Bellosguardo

Torre di Bellosguardo
4.0 star property
Santo Spirito
9.0 out of 10, Wonderful, (103 reviews)
"Beautiful property and wonderful staff."
United States
Brad
The price is €551
includes taxes & fees
18 Apr - 19 Apr
Torre di Bellosguardo

Mamo Florence - Maddalena Apartment

Mamo Florence - Maddalena Apartment
Santo Spirito
8.8 out of 10, Excellent, (3 reviews)
"As advertised, the stairs to reach the apartment were quite a work out. The is a nice clothes washing machine but no dryer, so plan for the provided drying rack. Everything was very nice!"
United States
Geoff
The price is €243
includes taxes & fees
4 May - 5 May
Mamo Florence - Maddalena Apartment

Oltrarno Splendid

Oltrarno Splendid
Santo Spirito
10.0 out of 10, Exceptional, (116 reviews)
"Fabulous place to stay"
United Kingdom
Kenneth
The price is €427
includes taxes & fees
20 Apr - 21 Apr
Oltrarno Splendid

SPIRIT OF FLORENCE Boutique Rooms

SPIRIT OF FLORENCE Boutique Rooms
Santo Spirito
10.0 out of 10, Exceptional, (25 reviews)
"Great place to stay for our visit to Florence. Walking distance to everything but in quiet neighborhood. Staff are very friendly and helpful. "
United States
Wendy
The price is €379
includes taxes & fees
13 May - 14 May
SPIRIT OF FLORENCE Boutique Rooms

Hotel Firenze 2000

Hotel Firenze 2000
2.0 star property
Santo Spirito
7.2 out of 10, Good, (194 reviews)
"The staff was wonderful and very helpful; 24 hr service ! The room was very clean and breakfast was plentiful. Great location if you don’t mind a short walk to the historic town center ; would definitely recommend."
Canada
Josee
The price is €119
includes taxes & fees
21 Apr - 22 Apr
Hotel Firenze 2000

Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments
Santo Spirito
9.8 out of 10, Exceptional, (142 reviews)
"Claudia was a great hostess who greeted us at the door and explained the room and comings and goings. She was gracious to hold our luggage on our last day before departing by train. "
United States
Anita
The price is €144
includes taxes & fees
19 Apr - 20 Apr
Drom Florence Rooms & Apartments

Hotel Horto Convento

Hotel Horto Convento
4.0 star property
Santo Spirito
9.8 out of 10, Exceptional, (637 reviews)
"Lovely location, staff were great"
United Kingdom
Martin
The price is €336
includes taxes & fees
30 Apr - 1 May
Hotel Horto Convento

Appartamenti degli Artisti by Mmega

Appartamenti degli Artisti by Mmega
Santo Spirito
8.4 out of 10, Very good, (33 reviews)
"Nice location with easy access to bus stops. Close to good restaurants and bars. "
United States
Prasanna
The price is €185
includes taxes & fees
4 May - 5 May
Appartamenti degli Artisti by Mmega

Palazzo D'Oltrarno - Residenza D'Epoca

Palazzo D'Oltrarno - Residenza D'Epoca
Santo Spirito
9.6 out of 10, Exceptional, (48 reviews)
"Excellent place to stay!"
United States
Diane
The price is €250
includes taxes & fees
20 Apr - 21 Apr
Palazzo D'Oltrarno - Residenza D'Epoca

Soggiorno Alessandra

Soggiorno Alessandra
Santo Spirito
8.6 out of 10, Excellent, (86 reviews)
"Alessandra is an amazing host, we had a perfect stay! The apartment is in excellent condition and very clean! "
United States
Elias
The price is €173
includes taxes & fees
21 Apr - 22 Apr
Soggiorno Alessandra

Home in Florence

Home in Florence
Santo Spirito
9.0 out of 10, Wonderful, (72 reviews)
"Lovely room and the people running the place were friendly and efficient "
United Kingdom
Thomas
The price is €120
includes taxes & fees
19 Apr - 20 Apr
Home in Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Spirito

Find the best Santo Spirito areas for the activities you enjoy most. Learn more about Santo Spirito
Learn more about Santo Spirito

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Piazza di Santa Maria Novella while you're exploring the neighbourhood.

San Giovanni

If you're spending some time in San Giovanni, Cathedral of Santa Maria del Fiore and Piazza della Repubblica are top sights worth seeing.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Santa Croce

Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top Santo Spirito Hotel Reviews

Find out more about Santo Spirito

Top reasons to visit Santo Spirito

  • Piazza Santo Spirito: This picturesque square captures the essence of authentic Florence, offering stunning architecture and a vibrant atmosphere.
  • Cultural Experiences: Santo Spirito is rich in artistic spirit, featuring trendy cafés and secluded corners perfect for relaxation.
  • Historic Churches: Explore beautiful historic churches that reflect the area's profound cultural heritage.
  • Public Market: Enjoy the lively public market, ideal for shopping and sampling local delicacies.
  • Varied Accommodations: Choose from charming hotels and bed and breakfasts that blend comfort with Italian flair.

Find great hotels near Santo Spirito

Discover a charming selection of hotel accommodations in Santo Spirito, Florence, where comfort meets Italian flair. Whether you prefer a cosy bed and breakfast or a stylish hotel, you'll find options catering to pet-friendly stays and city-themed experiences. With accessible hotels and the boutique Ad Astra Suites, your visit promises to be both delightful and convenient, making it the perfect base for exploring the enchanting streets of Tuscany.

  • The Social Hub Florence Lavagnini: This vibrant 4-star hotel caters to the modern traveller seeking a blend of city life, business efficiency, and adventure. Located approximately 1.6km from Santo Spirito, it features a variety of business amenities including a fully equipped Business Centre, meeting rooms, and co-working spaces. The hotel also offers exciting adventure sports and recreational activities both onsite and nearby, making it ideal for those looking to explore Florence's dynamic urban landscape. With its prime city centre location, The Social Hub is perfect for guests who want to balance work and play during their stay.
  • B&B Hotel Firenze Pitti Palace al Ponte Vecchio: Situated a mere 1.3km from Santo Spirito, this charming 4-star hotel is a family-friendly haven in the heart of Florence's shopping district. It offers a delightful mix of adventure and leisure, with nearby bicycle rentals for those keen on exploring the picturesque surroundings. The hotel also provides amenities for children, including onsite babysitting services. Guests appreciate the hotel's proximity to shopping and dining, making it a convenient base for families and adventure seekers alike, eager to uncover the treasures of Florence.
  • Grand Hotel Cavour: This elegant 4-star hotel is located approximately 1.6km from Santo Spirito in Florence's bustling shopping district. Ideal for families, the Grand Hotel Cavour offers various child-friendly amenities, including in-room and onsite babysitting services. Guests are drawn to its sophisticated atmosphere and the convenience of being close to Florence's cultural landmarks and shopping opportunities. With a perfect blend of comfort and accessibility, this hotel ensures that families can enjoy a memorable stay while exploring the enchanting city of Florence.

Where to stay near Santo Spirito

Santo Spirito, a charming neighbourhood in Florence, offers a delightful blend of culture and history. Wander around the picturesque Piazza Santo Spirito, where the architectural beauty captures the essence of authentic Florence. Experience the artistic spirit that permeates the area, with its trendy cafés and secluded corners perfect for relaxation. This vibrant district promises a unique atmosphere, showcasing the artistry of Florence, making it an ideal destination for families and culture enthusiasts alike.

  • Florence: As the capital of Tuscany, Florence is a cultural epicentre brimming with art, history, and architectural wonders. Situated around Santo Spirito, it offers a year-round vibrant atmosphere, with peak visitor numbers in March to April and September. Visitors flock here for immersive cultural experiences, family-friendly activities, and outdoor explorations. Key highlights include the historic centre, where you can marvel at landmarks such as the iconic Florence Cathedral and Ponte Vecchio, alongside bustling markets that showcase local crafts and delicacies. The city's charm is further enhanced by its picturesque streets, ideal for leisurely strolls.
  • Duomo: Just 1.4km from Santo Spirito, the Duomo neighbourhood is home to Florence's magnificent cathedral, which boasts stunning Renaissance architecture and a striking dome. This area sees a peak in visitors from July to September, drawn by its cultural offerings and outdoor spaces. In addition to the cathedral, Duomo features quaint shops and vibrant public markets, making it a delightful spot for both shopping and dining. The surrounding historic sites provide a glimpse into Florence's rich past, ensuring that every corner of Duomo tells a story.
  • Santa Maria Novella: Also located 1.4km from Santo Spirito, Santa Maria Novella is renowned for its impressive church of the same name and stunning frescoes. This neighbourhood welcomes a steady stream of tourists, especially during the spring and autumn months. Visitors here can explore charming markets, indulge in shopping, and enjoy nearby historic sites. The area is perfect for family outings, with plenty of outdoor spaces to relax and soak in the vibrant atmosphere. Its proximity to central Florence makes it an excellent base for exploration.

Things to do near Santo Spirito

Santo Spirito in Florence is perfect for culture enthusiasts and families alike, offering a vibrant atmosphere with its public market and shopping areas. Visitors can enjoy antique fairs, discover additional sights, and indulge in an aperitif in the picturesque piazza. This charming neighbourhood combines outdoor activities with rich cultural experiences, making it a delightful destination for all.

Shopping

Santo Spirito offers a delightful shopping experience with nearby gems like Central Market, 1.6km away, boasting a vibrant atmosphere, and Pitti Vintage, just 966m away, perfect for unique finds. Don’t miss Mercato di Sant'Ambrogio, located 3.2km away, for an authentic local market vibe.

Recreation

The Nelson Mandela Forum offers a relaxing atmosphere, perfect for unwinding and rejuvenation. The Stadio Artemio Franchi provides a vibrant sports environment, ideal for both spectators and participants. Meanwhile, Costoli Pool is perfect for families, featuring outdoor swimming and recreational activities amidst a lively setting.

Adventure

Experience the thrill of FiesoleBike Day Tours, located 1.6km from Santo Spirito, offering exhilarating outdoor cycling adventures. For motorsport enthusiasts, the Mugello Circuit, 27.4km away, provides an adrenaline-pumping racing experience. Alternatively, explore the scenic hiking trails at Parco di Montececeri, situated 6.4km from the centre.

Nightlife

Experience the vibrant nightlife in Santo Spirito by visiting Teatro Verdi and Teatro della Pergola for cultural performances that exude romance and family-friendly entertainment. Don't miss the Arcetri Observatory for a unique cosmic experience that adds to the lively atmosphere of this enchanting neighbourhood.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santo Spirito

To save money on your trip to Santo Spirito, consider visiting during the off-peak months of January to February or November for lower accommodation rates. Booking your hotel about a month in advance can secure better deals, and Monday is the cheapest day to stay. Utilise Expedia’s search tool to find budget-friendly options, and consider packages that combine flights and activities for additional savings. Explore the area on foot to save on transport costs, as many attractions are within walking distance.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Santo Spirito are January to February and November, where the prices are slightly lower. This is in comparison to May to June and September, where prices are slightly higher.
  • The best time to book a hotel: Book your hotel around Santo Spirito about 1 month out to secure some of the cheapest prices. If you're the spontaneous type, Expedia's last minute deals and discounts are indicated via the green label below the price.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Santo Spirito is Monday. The most expensive day to stay around Santo Spirito is Friday.
  • Find cheap hotels on Expedia: Expedia's search tool enables you to specify your budget, preferred location, and additional preferences. You can organise your search results to display prices from lowest to highest, ensuring you find the most affordable hotels first. Furthermore, you have the option to refine your selections by hotel type; for instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly hotels that are available for booking.
  • Consider bundling your trip: You can potentially reduce costs by combining your hotel stay in Santo Spirito with your flights and activities through an Expedia package.

Find the best attractions near Santo Spirito

Santo Spirito is an ideal destination for cultural, family, and outdoor holidays. Visitors can explore a variety of attractions, including picturesque piazzas, historic churches, and palatial buildings. The area offers a rich tapestry of experiences that cater to those seeking cultural immersion, family-friendly activities, and a taste of city life. A visit to Santo Spirito promises to be both enriching and enjoyable.

  • Uffizi Gallery: Home to an astounding collection of Renaissance art, the Uffizi Gallery is a cultural treasure trove. Located 1.4km from Santo Spirito, visitors can marvel at masterpieces by Botticelli and Michelangelo, all within a stunning architectural setting.
  • Cathedral of Santa Maria del Fiore: This magnificent cathedral, situated 1.6km away, is renowned for its stunning dome designed by Brunelleschi. Its intricate façade and breathtaking interiors reflect the rich history and artistry of Florence, making it a must-see.
  • Ponte Vecchio: Just 1.3km from Santo Spirito, this iconic medieval bridge is famous for its picturesque shops and vibrant atmosphere. Stroll along and enjoy the stunning views of the Arno River, immersing yourself in the local charm.

Best time to go to Santo Spirito

The best time to visit Santo Spirito is dependant on what kind of holiday you are seeking. July and August are its hottest month on average. At the time of August, visitor numbers are moderately high and weather is sunny. January is its coolest month on average. At this time, visitor numbers are moderately low and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January41.4°F (5.2°C)Light RainMostly SunnyModerately LowSlightly Low
February43.0°F (6.1°C)Light RainMostly SunnyModerately LowSlightly Low
March47.8°F (8.8°C)Light RainMostly SunnyAverageAverage
April54.3°F (12.4°C)Light RainMostly SunnyAverageAverage
May60.4°F (15.8°C)Light RainMostly SunnyAverageSlightly High
June69.6°F (20.9°C)Light RainSunnyAverageSlightly High
July75.2°F (24.0°C)No RainSunnyModerately HighAverage
August75.2°F (24.0°C)No RainSunnyModerately HighAverage
September67.3°F (19.6°C)Light RainMostly SunnyModerately HighSlightly High
October58.8°F (14.9°C)Light RainMostly SunnyAverageAverage
November50.2°F (10.1°C)Light RainMostly SunnyAverageSlightly Low
December43.5°F (6.4°C)Light RainMostly SunnyModerately LowAverage

The nearest major airports for your trip to Santo Spirito

Travelling to Santo Spirito, Florence, is convenient via several major airports. Florence Airport (FLR-Peretola) is a mere 4.8km away, with notable hotels like the 5-star Palazzo Montebello and Hotel Lungarno, both offering shuttle services. Bologna Airport (BLQ-Guglielmo Marconi) is located 54.8km from Santo Spirito, with excellent accommodations such as the Grand Hotel Majestic già Baglioni and Starhotels Excelsior, which provide shuttle services for easy access. Pisa Airport (PSA-Galileo Galilei) is 67.6km away, with luxurious options like Bagni di Pisa Palace & Thermal Spa and Pisa Tower Plaza, both offering shuttle transfers. Enjoy your stay in this exquisite Tuscan locale.

Frequently asked questions

What is Santo Spirito like?
Santo Spirito is a trendy neighbourhood known for its stunning river views. Make sure that you visit Piazza Santo Spirito and Santo Spirito Basilica as part of your Santo Spirito travel plans.
What's a favourite place to stay in Santo Spirito?
Based on our traveller data, Hotel Horto Convento is one of the top choices for your stay in Santo Spirito. This hotel is a short 14-minute walk from Piazza di Santa Maria Novella, and it offers free breakfast and a bar. Other good options for your stay in the neighbourhood include Palazzo Mannaioni Suites and La Torre Del Cestello.
How many hotels can I expect to find in the Santo Spirito area?
Expedia has 497 hotels and other accommodation options in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.
If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then filter by "fully refundable" to get top deals in Santo Spirito.
What can I see and do in this Florence neighbourhood?
Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighbourhood, Piazza Santo Spirito and Santo Spirito Basilica are some other places worth a visit. Piazza di Santa Maria Novella and Cathedral of Santa Maria del Fiore are some popular places to visit in the area around Santo Spirito. When you're sightseeing in Florence, Piazza del Carmine and Santa Maria della Carmine are also worth a stop.

Explore a world of travel with Expedia