A grand church interior with high vaulted ceilings, large columns, and a central altar.

Florence Hotel Guide. Hotels in Santo Spirito, Florence, Italy

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Our top choices for Santo Spirito hotels

1. Hotel Horto Convento

Hotel Horto Convento
4.0 star property
Santo Spirito
9.8 out of 10, Exceptional, (718 reviews)
"Great place, and the front desk gentleman was very helpful and kind all the time."
United States
adelio
The price is €279
includes taxes & fees
2 Sept - 3 Sept
Hotel Horto Convento

2. UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze
4.0 star property
Santo Spirito
8.4 out of 10, Very good, (1,003 reviews)
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Mexico
Jose Pablo
The price is €145
includes taxes & fees
4 Sept - 5 Sept
UNA Hotels Vittoria Firenze

3. La Torre Del Cestello

La Torre Del Cestello
Santo Spirito
9.2 out of 10, Wonderful, (303 reviews)
"Clean room friendly staff definitely be back"
United States
IVAN
The price is €199
includes taxes & fees
4 Sept - 5 Sept
La Torre Del Cestello

4. Palazzo Oliveto

Palazzo Oliveto
Santo Spirito
7.6 out of 10, Good, (106 reviews)
"I really enjoyed my stay here. The host was also extremely kind and helpful."
Belgium
Mary Mariam
The price is €105
includes taxes & fees
8 Sept - 9 Sept
Palazzo Oliveto

5. Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie
Santo Spirito
8.8 out of 10, Excellent, (237 reviews)
"liked the location and the sensible modernizations - had a nice spacious and comfortable room. Appreciated the air conditioning and friendly staff - plumbing could have been better. Thankfully, there was a lift to our 2nd floor guestroom. The food was pretty good for bulk catering."
Canada
David
The price is €120
includes taxes & fees
7 Sept - 8 Sept
Foresteria Valdese di Firenze - Casa per Ferie

6. 1900 Artevita

1900 Artevita
Santo Spirito
8.8 out of 10, Excellent, (203 reviews)
"Had a wonderful stay the host are very kind ladies. Place is very cute and clean and in a good location."
United States
Selena
The price is €114
includes taxes & fees
3 Sept - 4 Sept
1900 Artevita

7. Pindemonte Garden by MMega

Pindemonte Garden by MMega
Santo Spirito
The price is €227
includes taxes & fees
5 Sept - 6 Sept
Pindemonte Garden by MMega

8. Hotel Firenze 2000

Hotel Firenze 2000
2.0 star property
Santo Spirito
7.2 out of 10, Good, (201 reviews)
"This was a quaint little hotel. It was has a really friendly vibe. It’s a bit dated, but it only adds to its charm. I would return to this hotel. "
United States
Martin
The price is €92
includes taxes & fees
2 Sept - 3 Sept
Hotel Firenze 2000

9. La Fonderia Firenze

La Fonderia Firenze
Santo Spirito
9.6 out of 10, Exceptional, (185 reviews)
"Really nice, handy location"
United Kingdom
Kate
The price is €188
includes taxes & fees
7 Sept - 8 Sept
La Fonderia Firenze

10. Appartamenti degli Artisti by Mmega

Appartamenti degli Artisti by Mmega
Santo Spirito
8.6 out of 10, Excellent, (44 reviews)
"We stayed with our children and the space was excellent and the location was close enough to walk to everything. "
United States
Juliet
The price is €161
includes taxes & fees
2 Sept - 3 Sept
Appartamenti degli Artisti by Mmega

11. B&B Mia Palace

B&B Mia Palace
Santo Spirito
8.4 out of 10, Very good, (123 reviews)
"Breakfast was excellent and what a lovely host. "
United Kingdom
Wayne
The price is €116
includes taxes & fees
2 Sept - 3 Sept
B&B Mia Palace

12. Ottantotto Firenze

Ottantotto Firenze
Santo Spirito
9.6 out of 10, Exceptional, (176 reviews)
"Quaint boutique hotel in great location. Clean comfortable room and nice breakfast. Wonderful restaurant almost next door and close to train station. Highly recommend."
United States
Timothy
Ottantotto Firenze

13. Vettori Hideaway by MMega

Vettori Hideaway by MMega
Santo Spirito
The price is €175
includes taxes & fees
5 Sept - 6 Sept
Vettori Hideaway by MMega

14. L'Antica Porta Boutique B&B

L'Antica Porta Boutique B&B
Santo Spirito
8.6 out of 10, Excellent, (28 reviews)
"Very goord place to stay"
United States
Victor
The price is €98
includes taxes & fees
2 Sept - 3 Sept
L'Antica Porta Boutique B&B

15. Casa Santo Nome di Gesù

Casa Santo Nome di Gesù
Santo Spirito
8.8 out of 10, Excellent, (381 reviews)
"Beautiful hotel in great location. Staff really helpful with local knowledge. Communal fridge available at reception, which was great for storing drinks."
United Kingdom
Rebecca
The price is €180
includes taxes & fees
14 Sept - 15 Sept
Casa Santo Nome di Gesù

16. Campuccio Terrace by Mmega

Campuccio Terrace by Mmega
Santo Spirito
7.4 out of 10, Good, (6 reviews)
"The apartment was charming with a beautiful terrace. It was very clean, quiet, and easy access to local attractions. Our only complaint was that the fan was broken and the AC unit could not bring temperature down below 31, although we came during a heatwave. The stairs are a bit treacherous and there are many of them. It was not a problem for us but just a heads up to future guests."
United States
Anonymous traveller
The price is €171
includes taxes & fees
13 Sept - 14 Sept
Campuccio Terrace by Mmega

17. Lovely Campuccio by MMega

Lovely Campuccio by MMega
Santo Spirito
The price is €171
includes taxes & fees
8 Sept - 9 Sept
Lovely Campuccio by MMega

18. Residenza D'Epoca Al Numero 8

Residenza D'Epoca Al Numero 8
Santo Spirito
9.0 out of 10, Wonderful, (169 reviews)
"Excellent place"
United States
Laura Patricia
The price is €247
includes taxes & fees
6 Sept - 7 Sept
Residenza D'Epoca Al Numero 8

19. Fuori le Mura di San Frediano - Flo Apartments

Fuori le Mura di San Frediano - Flo Apartments
Santo Spirito
The price is €293
includes taxes & fees
6 Sept - 7 Sept
Fuori le Mura di San Frediano - Flo Apartments

20. Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments
Santo Spirito
9.8 out of 10, Exceptional, (152 reviews)
"We had a very nice stay. Claudia was very friendly and service minded The place serves continental breakfast - and is a good idea to supplement it a little bit! Nice and quiet area, where you can walk to most things We can only recommend it Else Marie Hansen May 2026"
Denmark
Else Marie
The price is €182
includes taxes & fees
13 Sept - 14 Sept
Drom Florence Rooms & Apartments
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Spirito

Find the best Santo Spirito areas for the activities you enjoy most. Learn more about Santo Spirito
Learn more about Santo Spirito

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Piazza di Santa Maria Novella while you're exploring the neighbourhood.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

San Giovanni

If you're spending some time in San Giovanni, Cathedral of Santa Maria del Fiore and Piazza della Repubblica are top sights worth seeing.

Santa Croce

Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top Santo Spirito Hotel Reviews

Find out more about Santo Spirito

Top reasons to visit Santo Spirito

  • Piazza Santo Spirito: This lively square is the heart of the neighbourhood, bustling with local life and creativity.
  • Historic Church of San Spirito: Explore this stunning church, a gem of Renaissance architecture and art.
  • Wine Tours: Experience Tuscany's exquisite wines through delightful local tours.
  • Charming Accommodation: Enjoy a range of unique lodging options, from stylish lofts to welcoming bed & breakfasts.
  • Scenic Strolls: Wander quaint streets and enjoy picturesque views along the nearby Arno River.

Find great hotels near Santo Spirito

Discover the charming accommodation options in Santo Spirito, Florence, where a delightful mix of hotels and bed & breakfasts await. Whether you're seeking a pet-friendly retreat or a stylish loft adorned with antique furniture, you'll find a variety of choices to suit your taste. Enjoy the vibrant atmosphere of the area, with close proximity to iconic sites like Palazzo Ridolfi and the masterpieces of Fra Bartolomeo, ensuring an unforgettable Tuscan getaway.

  • Hotel Spadai: Hotel Spadai is a splendid 4-star hotel with a remarkable guest rating of 9.8 out of 10, located approximately 1.6km from Santo Spirito. This accommodation is ideal for those seeking an adventurous yet romantic city-themed getaway. Guests can indulge in a variety of onsite adventure sports and recreational activities. The hotel also offers enticing romance packages, including winery tours and limited-hour room service for intimate dining experiences. For relaxation, visitors can unwind with spa amenities such as detoxification wraps, massages, and couples' treatment rooms, alongside a full-service spa and Turkish bath. Its central location enhances the overall romantic atmosphere, making it a charming choice for couples.
  • B&B Hotel Firenze Laurus al Duomo: With a guest rating of 9.2 out of 10, B&B Hotel Firenze Laurus al Duomo is a delightful 4-star accommodation situated just 1.4km from Santo Spirito. This property is tailored for city enthusiasts and shopping aficionados, featuring a pet-friendly policy that allows certain pets on-site. The hotel is conveniently located in a bustling shopping district, perfect for those looking to explore Florence’s vibrant retail scene. Amenities such as a waived fee for service animals, along with specific pet policies, ensure a comfortable stay for both travellers and their furry companions.
  • Hotel Albani Firenze: Hotel Albani Firenze is another 4-star option boasting a guest rating of 9.2 out of 10, located around 1.4km from Santo Spirito. This hotel focuses on providing a family-friendly environment, offering various services and amenities to cater to children. Features such as onsite babysitting and in-room childcare options (for a fee) make it an excellent choice for families looking to explore the beautiful city of Florence together. The welcoming atmosphere and family-centric services create a pleasant experience for guests of all ages.

Where to stay near Santo Spirito

Exploring Santo Spirito in Florence offers a delightful blend of culture and charm. This trendy neighbourhood boasts the picturesque Piazza Santo Spirito, a hub of local life and creativity. Immerse yourself in the rich history of the Florentine Renaissance while wandering its quaint streets. Just a stone’s throw away, you'll discover the romantic allure of the Arno River and the serene beauty of nearby attractions, making it the perfect base for a relaxing Tuscan getaway.

  • Arcetri: Nestled approximately 1.6km from Santo Spirito, Arcetri offers a charming village atmosphere that blends culture with outdoor experiences. This area attracts visitors seeking a tranquil escape, especially during peak seasons in April and from June to July. The local highlights include educational venues, shopping areas, and a relaxing spa. Explore the picturesque piazza square, historic places, and notable monuments that showcase the rich heritage of this quaint village, making it a delightful stop for those interested in both leisure and cultural immersion.
  • San Lorenzo: Located about 1.6km from Santo Spirito, San Lorenzo is a vibrant neighbourhood well-known for its cultural and business-oriented experiences. The area is particularly lively from July through September, drawing in crowds eager to explore the bustling public market and other educational venues. Visitors can enjoy the lively atmosphere of piazza squares and historic spots that define this vibrant community. San Lorenzo’s charm lies in its ability to blend traditional Italian culture with modern urban life, providing a unique experience for every traveller.
  • Santa Croce: Situated around 3.2km from Santo Spirito, Santa Croce is a neighbourhood that remains lively throughout the year. With peak visitor numbers in March, April, and October, it offers a rich cultural experience well-suited for families. The area boasts a variety of markets and shopping districts, making it a perfect destination for those looking to indulge in local flavours and crafts. Notable attractions include the picturesque piazza square, historic landmarks, and a vibrant tourist precinct, ensuring that Santa Croce is a must-visit on your Florentine itinerary.

Things to do near Santo Spirito

Shopping

In Santo Spirito, explore local shops and artisan boutiques that showcase unique gifts and souvenirs. Visit the bustling Mercato di Santo Spirito for fresh produce and handmade items, or stroll through charming streets lined with independent stores, offering a delightful shopping experience in the heart of Florence.

Recreation

In Santo Spirito, indulge in rejuvenating treatments at the luxurious Spa at Hotel Brunelleschi, set in a historic building. For a unique experience, visit the tranquil Yoga in Florence studio, where you can participate in calming classes surrounded by the beauty of Tuscany.

Adventure

At Mugello Circuit, located 27.4km from Santo Spirito, thrill-seekers can indulge in exhilarating motor racing experiences. With its vibrant atmosphere, the circuit offers an exciting backdrop for adrenaline-fuelled events, making it a must-visit for motorsport enthusiasts.

Nightlife

Santo Spirito boasts a vibrant nightlife, with lively bars and intimate venues. Enjoy a relaxed evening at the local wine bars, or dance the night away at trendy clubs. The atmosphere is filled with friendly locals and fellow travellers, creating an inviting and memorable experience.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santo Spirito

To save money on your trip to Santo Spirito, consider visiting during the off-peak months of January to February or November for lower accommodation rates. Booking your hotel about a month in advance can secure better deals, and Monday is the cheapest day to stay. Utilise Expedia’s search tool to find budget-friendly options, and consider packages that combine flights and activities for additional savings. Explore the area on foot to save on transport costs, as many attractions are within walking distance.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Santo Spirito are January to February and November, where the prices are slightly lower. This is in comparison to May to June and September, where prices are slightly higher.
  • The best time to book a hotel: Book your hotel around Santo Spirito about 1 month out to secure some of the cheapest prices. If you're the spontaneous type, Expedia's last minute deals and discounts are indicated via the green label below the price.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Santo Spirito is Monday. The most expensive day to stay around Santo Spirito is Friday.
  • Find cheap hotels on Expedia: Expedia's search tool enables you to specify your budget, preferred location, and additional preferences. You can organise your search results to display prices from lowest to highest, ensuring you find the most affordable hotels first. Furthermore, you have the option to refine your selections by hotel type; for instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly hotels that are available for booking.
  • Consider bundling your trip: You can potentially reduce costs by combining your hotel stay in Santo Spirito with your flights and activities through an Expedia package.

Find the best attractions near Santo Spirito

Santo Spirito in Florence, Tuscany, is ideal for culture, city, and outdoor enthusiasts. Visitors can explore notable attractions such as the charming Santo Spirito Square, the historic church of San Spirito, and various palaces. This vibrant area caters to travellers seeking cultural experiences, family activities, and picturesque cityscapes, making it a perfect destination for an enriching holiday.

  • Piazza della Signoria: A vibrant hub of Florentine life, this historic piazza offers a stunning open-air museum experience, featuring remarkable sculptures such as Michelangelo's David replica and the imposing Palazzo Vecchio. The lively atmosphere and nearby cafés invite leisurely exploration.
  • Cathedral of Santa Maria del Fiore: Known for its magnificent dome designed by Brunelleschi, this iconic cathedral showcases exquisite Gothic architecture. Inside, visitors can admire stunning frescoes and intricate details that reflect the rich cultural heritage of Florence.
  • Ponte Vecchio: This historic bridge, adorned with charming jewellery shops, provides picturesque views of the Arno River. Its unique architecture and vibrant atmosphere make it a delightful spot for a leisurely stroll or a memorable photograph.

Best time to go to Santo Spirito

The best time to visit Santo Spirito is dependent on what kind of holiday you are seeking. July and August are its hottest month on average. At the time of August, visitor numbers are moderately high and weather is sunny. January is its coolest month on average. At this time, visitor numbers are moderately low and weather is mostly sunny with light rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January41.4°F (5.2°C)Light RainMostly SunnyModerately LowSlightly Low
February43.0°F (6.1°C)Light RainMostly SunnyModerately LowSlightly Low
March47.8°F (8.8°C)Light RainMostly SunnyAverageAverage
April54.3°F (12.4°C)Light RainMostly SunnyAverageAverage
May60.4°F (15.8°C)Light RainMostly SunnyAverageSlightly High
June69.6°F (20.9°C)Light RainSunnyAverageSlightly High
July75.2°F (24.0°C)No RainSunnyModerately HighAverage
August75.2°F (24.0°C)No RainSunnyModerately HighAverage
September67.3°F (19.6°C)Light RainMostly SunnyModerately HighSlightly High
October58.8°F (14.9°C)Light RainMostly SunnyAverageAverage
November50.2°F (10.1°C)Light RainMostly SunnyAverageSlightly Low
December43.5°F (6.4°C)Light RainMostly SunnyModerately LowAverage

The nearest major airports for your trip to Santo Spirito

Travelling to Santo Spirito in Florence is convenient with three major airports nearby. Florence Airport (FLR-Peretola) is only 4.8km away, with luxurious options like the Villa Tolomei Hotel & Resort and Rocco Forte Hotel Savoy nearby. Pisa Airport (PSA-Galileo Galilei) is located 67.6km from Santo Spirito, with top hotels such as Toscana Charme Resort and Grand Hotel Bonanno offering shuttle services. Bologna Airport (BLQ-Guglielmo Marconi) is 85.3km distant, with the Starhotels Excelsior and I Portici Hotel providing transportation options. Each airport offers easy access to Santo Spirito, ensuring a seamless travel experience.

Frequently asked questions

What is Santo Spirito like?
Santo Spirito is a trendy neighbourhood known for its stunning river views. Make sure that you visit Piazza Santo Spirito and Santo Spirito Basilica as part of your Santo Spirito travel plans.
What's a favourite place to stay in Santo Spirito?
Based on our traveller data, Hotel Horto Convento is one of the top choices for your stay in Santo Spirito. This hotel is a short 14-minute walk from Piazza di Santa Maria Novella, and it offers free breakfast and a bar. Other good options for your stay in the neighbourhood include La Torre Del Cestello and UNA Hotels Vittoria Firenze.
How many hotels can I expect to find in the Santo Spirito area?
Expedia has 500 hotels and other accommodation options in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.
If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then filter by "fully refundable" to get top deals in Santo Spirito.
What can I see and do in this Florence neighbourhood?
Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighbourhood, Piazza Santo Spirito and Santo Spirito Basilica are some other places worth a visit. Piazza di Santa Maria Novella and Cathedral of Santa Maria del Fiore are some popular places to visit in the area around Santo Spirito. When you're sightseeing in Florence, Piazza del Carmine and Santa Maria della Carmine are also worth a stop.

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