
San Antonio Hotel Guide. Hotels in Jefferson, San Antonio, United States of America
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Jefferson hotels

1. Comfort Inn and Suites Near Medical Center
Comfort Inn and Suites Near Medical Center2.6 km from Jefferson
7.2 out of 10, Good, (2,398 reviews)
The price is €62
includes taxes & fees
15 Nov - 16 Nov

2. San Antonio Marriott Northwest Medical Center
San Antonio Marriott Northwest Medical CenterMedical Center District, 4.9 km from Jefferson
8.6 out of 10, Excellent, (1,194 reviews)
The price is €92
includes taxes & fees
5 Dec - 6 Dec

3. Courtyard by Marriott Medical Center San Antonio
Courtyard by Marriott Medical Center San AntonioMedical Center District, 7.1 km from Jefferson
8.8 out of 10, Excellent, (1,000 reviews)
The price is €95
includes taxes & fees
26 Nov - 27 Nov

4. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NWMedical Center District, 6.3 km from Jefferson
8.4 out of 10, Very good, (3,765 reviews)
The price is €94
includes taxes & fees
19 Nov - 20 Nov

5. Best Western Plus Downtown North
Best Western Plus Downtown North7.7 km from Jefferson
8.6 out of 10, Excellent, (1,000 reviews)
The price is €93
includes taxes & fees
12 Nov - 13 Nov

6. Hyatt Vacation Club at Wild Oak Ranch, San Antonio
Hyatt Vacation Club at Wild Oak Ranch, San AntonioFar West Side, 13.5 km from Jefferson
9.0 out of 10, Wonderful, (2,063 reviews)
The price is €116
includes taxes & fees
30 Nov - 1 Dec

7. AC Hotel by Marriott San Antonio Riverwalk
AC Hotel by Marriott San Antonio Riverwalk5.9 km from Jefferson
9.2 out of 10, Wonderful, (1,369 reviews)
The price is €121
includes taxes & fees
20 Nov - 21 Nov

8. Drury Inn & Suites San Antonio Northwest Medical Center
Drury Inn & Suites San Antonio Northwest Medical CenterMedical Center District, 8.1 km from Jefferson
9.2 out of 10, Wonderful, (1,522 reviews)
The price is €96
includes taxes & fees
9 Nov - 10 Nov

9. Hotel Gibbs Downtown Riverwalk
Hotel Gibbs Downtown RiverwalkDowntown San Antonio, 6.2 km from Jefferson
9.0 out of 10, Wonderful, (2,378 reviews)
The price is €89
includes taxes & fees
15 Nov - 16 Nov

10. Crockett Hotel
Crockett HotelDowntown San Antonio, 6.5 km from Jefferson
8.8 out of 10, Excellent, (2,837 reviews)
The price is €80
includes taxes & fees
15 Nov - 16 Nov

11. Holiday Inn Express San Antonio Rivercenter Area by IHG
Holiday Inn Express San Antonio Rivercenter Area by IHG7.5 km from Jefferson
8.8 out of 10, Excellent, (1,004 reviews)
The price is €95
includes taxes & fees
3 Dec - 4 Dec

12. Ramada by Wyndham San Antonio Near SeaWorld/Lackland AFB
Ramada by Wyndham San Antonio Near SeaWorld/Lackland AFB8.9 km from Jefferson
8.6 out of 10, Excellent, (1,002 reviews)
The price is €71
includes taxes & fees
19 Nov - 20 Nov

13. La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB
La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB9.8 km from Jefferson
9.2 out of 10, Wonderful, (1,168 reviews)
The price is €106
includes taxes & fees
9 Nov - 10 Nov

14. La Quinta Inn & Suites by Wyndham San Antonio Downtown
La Quinta Inn & Suites by Wyndham San Antonio DowntownArsenal, 6.1 km from Jefferson
9.0 out of 10, Wonderful, (3,683 reviews)
The price is €95
includes taxes & fees
24 Nov - 25 Nov

15. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
Heritage Inn & Suites San Antonio Airport, Trademark WyndhamUptown Central, 8.4 km from Jefferson
9.0 out of 10, Wonderful, (2,377 reviews)
The price is €84
includes taxes & fees
15 Nov - 16 Nov

16. Drury Plaza Hotel San Antonio Riverwalk
Drury Plaza Hotel San Antonio RiverwalkDowntown San Antonio, 6.1 km from Jefferson
9.4 out of 10, Exceptional, (5,470 reviews)
The price is €136
includes taxes & fees
15 Nov - 16 Nov

17. Best Western Plus Lackland Hotel & Suites
Best Western Plus Lackland Hotel & Suites13.3 km from Jefferson
8.6 out of 10, Excellent, (1,000 reviews)
The price is €97
includes taxes & fees
4 Dec - 5 Dec

18. Days Inn & Suites by Wyndham San Antonio near Frost Bank Center
Days Inn & Suites by Wyndham San Antonio near Frost Bank CenterArena District, 12.2 km from Jefferson
8.4 out of 10, Very good, (1,095 reviews)
The price is €62
includes taxes & fees
6 Dec - 7 Dec

19. Courtyard by Marriott San Antonio Lackland
Courtyard by Marriott San Antonio Lackland8.2 km from Jefferson
8.2 out of 10, Very good, (1,000 reviews)
The price is €86
includes taxes & fees
15 Nov - 16 Nov

20. Element by Marriott San Antonio Riverwalk
Element by Marriott San Antonio Riverwalk5.9 km from Jefferson
9.2 out of 10, Wonderful, (1,464 reviews)
The price is €117
includes taxes & fees
29 Nov - 30 Nov
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels in Jefferson
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB | 9.2 Wonderful 1,168 reviews | View | ||||||
![]() Courtyard by Marriott Medical Center San Antonio | 8.8 Excellent 1,000 reviews | View | ||||||
![]() Candlewood Suites San Antonio Lackland AFB Area by IHG | 9.2 Wonderful 974 reviews | View | ||||||
![]() Drury Inn & Suites San Antonio Northwest Medical Center | 9.2 Wonderful 1,522 reviews | View | ||||||
![]() Holiday Inn Express San Antonio-Airport by IHG | 9.4 Exceptional 1,005 reviews | View |
Where to stay in Jefferson
Find the best Jefferson areas for the activities you enjoy most.

Downtown San Antonio
Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Uptown Central
If you're spending some time in Uptown Central, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.

Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Medical Center District
While Medical Center District isn't home to many top sights, Wonderland of the Americas Mall and Huebner Oaks are some notable places to visit nearby.

Northwest Side
If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.
Top Jefferson Hotel Reviews

Hotel Valencia Riverwalk, Valencia Collection
10/10 Excellent
Frequently asked questions
Explore a world of travel with Expedia
- Alamo Heights Hotels
- Hotels near Alamo
- Best Western Hotels in Alamo Plaza
- Cheap Hotels in Alamo Plaza
- Drury Inn & Suites Hotels in Alamo Plaza
- Hotels near Alamodome
- Beacon Hill Hotels
- Blossoms Park Hotels
- Hotels near Blue Star Art Space Museum
- Boutique Hotels in Downtown San Antonio
- Cheap Hotels in Downtown San Antonio
- Downtown San Antonio Hotels
- Golf Hotels in East San Antonio
- East Terrell Hills Hotels
- Hotels near Henry B. González Convention Center
- Historic Garderns Hotels
- Hollywood Park Hotels
- Hotels near Lackland Air Force Base
- Hotels near Lackland Air Force Base Visitor Center
- Medical Center District Hotels
- Mission Trace Hotels
- Monticello Park Hotels
- Pearl District Hotels
- Hotels near River Walk
- B&B in San Antonio
- Cabin Rentals in San Antonio
- Guest Houses in San Antonio
- Resorts in San Antonio
- Adventure Sport Hotels in San Antonio
- Boutique Hotels in San Antonio
- Cheap Hotels in San Antonio
- Family Friendly Hotels in San Antonio
- Historic Hotels in San Antonio
- Hotels with Breakfast in San Antonio
- Hotels with Connecting Rooms in San Antonio
- Hotels with Yoga in San Antonio
- Lgbt-Friendly Hotels in San Antonio
- Luxury Hotels in San Antonio
- Romantic Hotels in San Antonio
- Starwood Capital Hotels in San Antonio
- San Antonio Hotels
- Hotels near San Antonio Intl.
- Motels in San Antonio
- Holiday Homes in San Antonio
- Villas in San Antonio
- Hotels near San Antonio Zoo and Aquarium
- Hotels near Six Flags Fiesta Texas
- South San Antonio Hotels
- Hotels near USAA Corporate Office Headquarters
- Windcrest Hotels
- Woodstone Hotels
- Flights to San Antonio
- Flights from Amarillo (AMA) to San Antonio (SAT)
- Flights from Ibiza (IBZ) to San Antonio (SAT)
- Flights from New York (JFK) to San Antonio (SAT)
- Flights from Las Vegas (LAS) to San Antonio (SAT)
- Flights from Madrid (MAD) to San Antonio (SAT)
- Flights from Mexico City (MEX) to San Antonio (SAT)
- Flights from Philadelphia (PHL) to San Antonio (SAT)
- Flights from Charlotte (QWG) to San Antonio (SAT)
- Flights from Shannon (SNN) to San Antonio (SAT)
- Alamo
- Visit Alamo Plaza
- Alamo Quarry Market
- Belmeade Park
- Bexar County Holidays
- Visit Bexar County
- Harry B Orem Stadium
- Ingram Park Mall
- Japanese Tea Gardens
- Visit Downtown San Antonio
- Visit King William
- Visit Main - Military Plaza
- Visit Midtown
- Visit Westfort
- San Antonio Zoo and Aquarium
- San Antonio Holidays
- Visit San Antonio
- San Pedro Driving Range & Par 3 Course
- Shops at Rivercenter
- Usaa Corporate Office Headquarters
- Car hire near Alamo
- Car hire near San Antonio
- Car hire in Dollar Rent A Car Calle De Diaz Del Castillo, 7
- Dollar Rent A Car Rental Cars in Alamo Plaza
- Foco Rental Cars in East San Antonio
- Goldcar rental Rental Cars in Alamo Plaza
- Hertz Rental Cars in Alamo Plaza
- Movida Rent A Car Rental Cars in Alamo Plaza
- Movida Rent A Car Rental Cars in East San Antonio
- Thrifty Car Rental Rental Cars in Alamo Plaza
- Thrifty Car Rental Rental Cars in East San Antonio


























































































