The Alamo, a historic building with a prominent arched entrance and a flagpole in front.

San Antonio Hotel Guide. Hotels in Jefferson, San Antonio, United States of America

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Our top choices for Jefferson hotels

1. Comfort Inn and Suites Near Medical Center

Comfort Inn and Suites Near Medical Center
2.5 star property
2.6 km from Jefferson
7.2 out of 10, Good, (2,398 reviews)
"Great hotel for the price, would stay again"
United States
Amy
The price is €62
includes taxes & fees
15 Nov - 16 Nov
Comfort Inn and Suites Near Medical Center

2. San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District, 4.9 km from Jefferson
8.6 out of 10, Excellent, (1,194 reviews)
"Room was clean, very friendly staff"
Canada
Hsiao Tung
The price is €92
includes taxes & fees
5 Dec - 6 Dec
San Antonio Marriott Northwest Medical Center

3. Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District, 7.1 km from Jefferson
8.8 out of 10, Excellent, (1,000 reviews)
"Great property, nice rooms"
United States
Francisca
The price is €95
includes taxes & fees
26 Nov - 27 Nov
Courtyard by Marriott Medical Center San Antonio

4. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District, 6.3 km from Jefferson
8.4 out of 10, Very good, (3,765 reviews)
"Great place to stay"
United States
Gilbert
The price is €94
includes taxes & fees
19 Nov - 20 Nov
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

5. Best Western Plus Downtown North

Best Western Plus Downtown North
2.5 star property
7.7 km from Jefferson
8.6 out of 10, Excellent, (1,000 reviews)
"Great stay!"
United States
Vanesa
The price is €93
includes taxes & fees
12 Nov - 13 Nov
Best Western Plus Downtown North

6. Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
3.5 star property
Far West Side, 13.5 km from Jefferson
9.0 out of 10, Wonderful, (2,063 reviews)
"Great resort"
United States
Evan
The price is €116
includes taxes & fees
30 Nov - 1 Dec
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

7. AC Hotel by Marriott San Antonio Riverwalk

AC Hotel by Marriott San Antonio Riverwalk
4.0 star property
5.9 km from Jefferson
9.2 out of 10, Wonderful, (1,369 reviews)
"Great hotel"
United States
Ricardo
The price is €121
includes taxes & fees
20 Nov - 21 Nov
AC Hotel by Marriott San Antonio Riverwalk

8. Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District, 8.1 km from Jefferson
9.2 out of 10, Wonderful, (1,522 reviews)
"Everything was great enjoyed our stay"
United States
Samuel
The price is €96
includes taxes & fees
9 Nov - 10 Nov
Drury Inn & Suites San Antonio Northwest Medical Center

9. Hotel Gibbs Downtown Riverwalk

Hotel Gibbs Downtown Riverwalk
2.0 star property
Downtown San Antonio, 6.2 km from Jefferson
9.0 out of 10, Wonderful, (2,378 reviews)
"Perfect location, excellent breakfast and beautifully decorated"
United States
Michael
The price is €89
includes taxes & fees
15 Nov - 16 Nov
Hotel Gibbs Downtown Riverwalk

10. Crockett Hotel

Crockett Hotel
3.0 star property
Downtown San Antonio, 6.5 km from Jefferson
8.8 out of 10, Excellent, (2,837 reviews)
"Great spot cool vibe"
United States
Anna
The price is €80
includes taxes & fees
15 Nov - 16 Nov
Crockett Hotel

11. Holiday Inn Express San Antonio Rivercenter Area by IHG

Holiday Inn Express San Antonio Rivercenter Area by IHG
2.5 star property
7.5 km from Jefferson
8.8 out of 10, Excellent, (1,004 reviews)
"Was a very good stay"
United States
Gumecindo
The price is €95
includes taxes & fees
3 Dec - 4 Dec
Holiday Inn Express San Antonio Rivercenter Area by IHG

12. Ramada by Wyndham San Antonio Near SeaWorld/Lackland AFB

Ramada by Wyndham San Antonio Near SeaWorld/Lackland AFB
2.5 star property
8.9 km from Jefferson
8.6 out of 10, Excellent, (1,002 reviews)
"Room was clean and staff was nice"
United States
Brian
The price is €71
includes taxes & fees
19 Nov - 20 Nov
Ramada by Wyndham San Antonio Near SeaWorld/Lackland AFB

13. La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB
3.0 star property
9.8 km from Jefferson
9.2 out of 10, Wonderful, (1,168 reviews)
"Great stay for Lackland Air Force Base."
United States
Lakesha
The price is €106
includes taxes & fees
9 Nov - 10 Nov
La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

14. La Quinta Inn & Suites by Wyndham San Antonio Downtown

La Quinta Inn & Suites by Wyndham San Antonio Downtown
3.0 star property
Arsenal, 6.1 km from Jefferson
9.0 out of 10, Wonderful, (3,683 reviews)
"Great room size and amenities."
United Kingdom
Natasha
The price is €95
includes taxes & fees
24 Nov - 25 Nov
La Quinta Inn & Suites by Wyndham San Antonio Downtown

15. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
2.5 star property
Uptown Central, 8.4 km from Jefferson
9.0 out of 10, Wonderful, (2,377 reviews)
"Great location near the airport."
United States
Elsa
The price is €84
includes taxes & fees
15 Nov - 16 Nov
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

16. Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk
4.0 star property
Downtown San Antonio, 6.1 km from Jefferson
9.4 out of 10, Exceptional, (5,470 reviews)
"Will definitely stay again!"
United States
Felicia
The price is €136
includes taxes & fees
15 Nov - 16 Nov
Drury Plaza Hotel San Antonio Riverwalk

17. Best Western Plus Lackland Hotel & Suites

Best Western Plus Lackland Hotel & Suites
2.5 star property
13.3 km from Jefferson
8.6 out of 10, Excellent, (1,000 reviews)
"Great cheap stay"
United States
Michael
The price is €97
includes taxes & fees
4 Dec - 5 Dec
Best Western Plus Lackland Hotel & Suites

18. Days Inn & Suites by Wyndham San Antonio near Frost Bank Center

Days Inn & Suites by Wyndham San Antonio near Frost Bank Center
2.5 star property
Arena District, 12.2 km from Jefferson
8.4 out of 10, Very good, (1,095 reviews)
"Always a clean and quiet place to stay."
United States
Samhandel
The price is €62
includes taxes & fees
6 Dec - 7 Dec
Days Inn & Suites by Wyndham San Antonio near Frost Bank Center

19. Courtyard by Marriott San Antonio Lackland

Courtyard by Marriott San Antonio Lackland
3.0 star property
8.2 km from Jefferson
8.2 out of 10, Very good, (1,000 reviews)
"Clean room, very roomy, we loved our stay"
United States
Jolynn
The price is €86
includes taxes & fees
15 Nov - 16 Nov
Courtyard by Marriott San Antonio Lackland

20. Element by Marriott San Antonio Riverwalk

Element by Marriott San Antonio Riverwalk
4.0 star property
5.9 km from Jefferson
9.2 out of 10, Wonderful, (1,464 reviews)
"Great breakfast and comfortable room"
United States
Crystal
The price is €117
includes taxes & fees
29 Nov - 30 Nov
Element by Marriott San Antonio Riverwalk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Jefferson

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A modern hotel with a prominent sign reading "LA QUINTA".
La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB
3.0 star property
9.2
Wonderful
1,168 reviews
View
A modern bar area with wooden bar counters, black bar stools, and pendant lighting.
Courtyard by Marriott Medical Center San Antonio
3.0 star property
8.8
Excellent
1,000 reviews
View
A hotel with a modern facade, multiple windows, and a well-lit entrance.
Candlewood Suites San Antonio Lackland AFB Area by IHG
2.5 star property
9.2
Wonderful
974 reviews
View
A spacious lobby with multiple seating areas, a central coffee table, and a view of the upper floors.
Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
9.2
Wonderful
1,522 reviews
View
A Holiday Inn Express reception desk with a modern design, featuring a large illuminated sign, a reception area, and a potted plant.
Holiday Inn Express San Antonio-Airport by IHG
2.5 star property
9.4
Exceptional
1,005 reviews
View

Where to stay in Jefferson

Find the best Jefferson areas for the activities you enjoy most.

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Uptown Central

If you're spending some time in Uptown Central, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Medical Center District

While Medical Center District isn't home to many top sights, Wonderland of the Americas Mall and Huebner Oaks are some notable places to visit nearby.

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.

Top Jefferson Hotel Reviews

Frequently asked questions

What is Jefferson like?
Travellers to San Antonio's Jefferson neighbourhood will be sure to enjoy a stay here. Consider a visit to Woodlawn Lake Park as part of your Jefferson travel plans.
How many hotels should I expect to find in Jefferson?
Expedia has 42 hotels and other accommodation options in Jefferson to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Jefferson, will I receive a refund?
Yes! Most hotel reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and get a refund within a 24-hour period of booking. Add dates, click "Search", then you can use the "fully refundable" filter to review the top deals on offer in Jefferson.
What are the top things to see and do in Jefferson?
Woodlawn Lake Park is an attraction you might want to check out while you're in Jefferson. While you're out sightseeing in San Antonio, make sure that you visit other sights such as Woodlawn Theater or The Starlighter.

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