San Diego Hotel Guide. Hotels in Otay Mesa, San Diego, United States of America

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21 Aug - 22 Aug
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Top Trending Hotels Near Otay Mesa, San Diego

Our top choices for Otay Mesa hotels

Quality Suites San Diego Otay Mesa
Desk, laptop workspace, blackout curtains, iron/ironing board

Quality Suites San Diego Otay Mesa

2.5 star property
7.2 out of 10, Good, (1000)
"Great location and spacious room "
The price is €105
includes taxes & fees
7 Sept - 8 Sept
Quality Suites San Diego Otay Mesa
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Exterior

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

2.5 star property
8.0 out of 10, Very good, (1433)
"Very good to stayed "
The price is €105
includes taxes & fees
27 Aug - 28 Aug
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Hotel Zindel
Terrace/patio

Hotel Zindel

2.0 star property
7.6 out of 10, Good, (525)
"Great stay "
Hotel Zindel
Palihotel San Diego Gaslamp Quarter
Rooftop terrace

Palihotel San Diego Gaslamp Quarter

4.0 star property
8.8 out of 10, Excellent, (1648)
"Enjoyed the stay !! "
The price is €104
includes taxes & fees
28 Aug - 29 Aug
Palihotel San Diego Gaslamp Quarter
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Exterior

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

3.0 star property
9.0 out of 10, Wonderful, (1071)
"We had a great stay!"
The price is €133
includes taxes & fees
26 Aug - 27 Aug
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Best Western Plus Marina Gateway Hotel
Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed)

Best Western Plus Marina Gateway Hotel

3.5 star property
9.2 out of 10, Wonderful, (3216)
"Enjoyed my stay"
The price is €127
includes taxes & fees
7 Sept - 8 Sept
Best Western Plus Marina Gateway Hotel
The Horton Grand, Downtown/Gaslamp Quarter
Serves dinner and happy hour

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
9.0 out of 10, Wonderful, (2459)
"We enjoyed our stay."
The Horton Grand, Downtown/Gaslamp Quarter
Sentral Gaslamp Quarter
Premium bedding, pillow-top beds, desk, laptop workspace

Sentral Gaslamp Quarter

3.0 star property
9.2 out of 10, Wonderful, (282)
"Amazing place to stay love it "
The price is €143
includes taxes & fees
24 Aug - 25 Aug
Sentral Gaslamp Quarter
Best Western Plus Suites Hotel Coronado Island
Outdoor pool, pool loungers

Best Western Plus Suites Hotel Coronado Island

2.5 star property
8.8 out of 10, Excellent, (1000)
"Very good location"
The price is €195
includes taxes & fees
1 Sept - 2 Sept
Best Western Plus Suites Hotel Coronado Island
Hard Rock Hotel San Diego
Outdoor pool

Hard Rock Hotel San Diego

4.0 star property
9.0 out of 10, Wonderful, (2809)
"Always an enjoyable stay"
The price is €204
includes taxes & fees
21 Sept - 22 Sept
Hard Rock Hotel San Diego
El Cordova Hotel on Coronado Island
Lobby

El Cordova Hotel on Coronado Island

3.5 star property
8.8 out of 10, Excellent, (1002)
"Loved our stay at El Cordova Hotel! The on-site restaurant was super convenient, the whole place had a cozy, homey vibe, and we were just minutes from Coronado Beach. Excellent experience all around!"
The price is €239
includes taxes & fees
4 Sept - 5 Sept
El Cordova Hotel on Coronado Island
Gaslamp Plaza Suites
Lobby

Gaslamp Plaza Suites

3.5 star property
8.8 out of 10, Excellent, (1002)
"Great place and location. Nice rooftop"
The price is €102
includes taxes & fees
27 Aug - 28 Aug
Gaslamp Plaza Suites
The Sofia Hotel
Front of property

The Sofia Hotel

3.5 star property
8.4 out of 10, Very good, (1524)
"Great Hotel. Very close to Little Italy, The Whaley House, The San Diego Zoo, and many more locations."
The Sofia Hotel
Loews Coronado Bay Resort
Exterior

Loews Coronado Bay Resort

4.0 star property
8.8 out of 10, Excellent, (1010)
"Great hotel, great location! Friendly staff, great pool area, close to many things. Would absolutely recommend and stay again!!! "
The price is €229
includes taxes & fees
1 Sept - 2 Sept
Loews Coronado Bay Resort
AC Hotel by Marriott San Diego Downtown Gaslamp Quarter
Lobby sitting area

AC Hotel by Marriott San Diego Downtown Gaslamp Quarter

4.0 star property
8.8 out of 10, Excellent, (898)
"Would definitely stay again!"
The price is €155
includes taxes & fees
26 Aug - 27 Aug
AC Hotel by Marriott San Diego Downtown Gaslamp Quarter
Staypineapple, Hotel Z, Gaslamp San Diego
Premium bedding, pillow-top beds, desk, blackout curtains

Staypineapple, Hotel Z, Gaslamp San Diego

3.0 star property
9.4 out of 10, Exceptional, (1001)
"Staff are nice and the property is situated in a great area. "
The price is €143
includes taxes & fees
26 Aug - 27 Aug
Staypineapple, Hotel Z, Gaslamp San Diego
San Diego Downtown Lodge
View from property

San Diego Downtown Lodge

2.0 star property
6.2 out of 10, (1002)
"The staffs are very helpful and friendly. The place is clean."
San Diego Downtown Lodge
Best Western Plus La Mesa San Diego
Lobby

Best Western Plus La Mesa San Diego

2.5 star property
8.2 out of 10, Very good, (1002)
"Staff was friendly, hotel was clean and breakfast was great"
The price is €101
includes taxes & fees
7 Sept - 8 Sept
Best Western Plus La Mesa San Diego
Days Inn by Wyndham San Diego-East/El Cajon
Standard Room, 1 King Bed, Smoking

Days Inn by Wyndham San Diego-East/El Cajon

2.0 star property
7.6 out of 10, Good, (1002)
"The hotel was great and the staff are more wonderful and also deserves five stars"
The price is €83
includes taxes & fees
7 Sept - 8 Sept
Days Inn by Wyndham San Diego-East/El Cajon
The Bristol Hotel San Diego
Property entrance

The Bristol Hotel San Diego

3.5 star property
8.4 out of 10, Very good, (1360)
"Great stay"
The Bristol Hotel San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa

Find the best Otay Mesa areas for the activities you enjoy most.

Downtown San Diego

2 out of top 10 points of interest in this area

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Belmont Park which includes rides and a garden

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Pacific Beach featuring a beach

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Crystal Pier while you're exploring the area.

Gaslamp Quarter featuring a city, signage and a bar

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Harlem of the West Sites – discover Gaslamp Quarter, a destination also famous for its shopping.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach.

Top Otay Mesa Hotel Reviews

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

10/10 Excellent
"It was a great hotel and very clean. I enjoyed my stay. "
Karen 1-night trip
Posted 1 day ago
Manchester Grand Hyatt San Diego

Frequently asked questions

What's it like in Otay Mesa?

Otay Mesa is a neighbourhood that travellers like for its beaches, restaurants and shopping.

Where is the best hotel for a stay in Otay Mesa?

Based on Expedia customer reviews, Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is the highest ranked property in Otay Mesa. This hotel offers free breakfast and an outdoor pool. Another top choice in the area is Quality Suites San Diego Otay Mesa.

If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?

Yes! Most room reservations are refundable provided that you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Add dates, click "Search", then filter by "fully refundable" to view top deals in Otay Mesa.

What is there to do in this San Diego neighbourhood?

A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.