San Diego Hotel Guide. Hotels in Otay Mesa, San Diego, United States of America

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27 Aug - 28 Aug
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28 Aug - 29 Aug
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29 Aug - 31 Aug
Next weekend
5 Sept - 7 Sept

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Top Trending Hotels Near Otay Mesa, San Diego

Our top choices for Otay Mesa hotels

Sycuan Casino Resort
3 outdoor pools, pool cabanas (surcharge), pool umbrellas

Sycuan Casino Resort

4.0 star property
9.2 out of 10, Wonderful, (1513)
"Love this place"
Sycuan Casino Resort
Hampton Inn & Suites San Diego Seaworld
Hypo-allergenic bedding, desk, laptop workspace, iron/ironing board

Hampton Inn & Suites San Diego Seaworld

2.5 star property
8.8 out of 10, Excellent, (12)
"The property was newly renovated. Clean nice decor. Love the furniture "
The price is €117
includes taxes & fees
2 Sept - 3 Sept
Hampton Inn & Suites San Diego Seaworld
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Exterior

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

2.5 star property
8.0 out of 10, Very good, (1447)
"Very good to stayed "
The price is €136
includes taxes & fees
28 Aug - 29 Aug
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Best Western San Diego Pacific Beach/Mission Bay
Outdoor pool

Best Western San Diego Pacific Beach/Mission Bay

2.5 star property
7.2 out of 10, Good, (1280)
"Excellent hotel !! "
The price is €79
includes taxes & fees
1 Sept - 2 Sept
Best Western San Diego Pacific Beach/Mission Bay
Quality Suites San Diego Otay Mesa
Desk, laptop workspace, blackout curtains, iron/ironing board

Quality Suites San Diego Otay Mesa

2.5 star property
7.2 out of 10, Good, (1005)
"Nice place. Clean and quiet. "
The price is €105
includes taxes & fees
21 Sept - 22 Sept
Quality Suites San Diego Otay Mesa
Ayres Hotel San Diego South - Chula Vista
Lobby lounge

Ayres Hotel San Diego South - Chula Vista

3.0 star property
9.8 out of 10, Exceptional, (1077)
"Prefect stay with the family. Would stay again and recommend to friends. "
The price is €159
includes taxes & fees
1 Sept - 2 Sept
Ayres Hotel San Diego South - Chula Vista
La Quinta Inn by Wyndham San Diego Chula Vista
Exterior

La Quinta Inn by Wyndham San Diego Chula Vista

3.0 star property
8.6 out of 10, Excellent, (1385)
"Great place to stay at , along with a good breakfast variety. Overall I'll stay here again"
The price is €99
includes taxes & fees
7 Sept - 8 Sept
La Quinta Inn by Wyndham San Diego Chula Vista
Super 8 by Wyndham El Cajon/San Diego
Lobby

Super 8 by Wyndham El Cajon/San Diego

2.0 star property
7.8 out of 10, Good, (1006)
"Great place "
The price is €75
includes taxes & fees
1 Sept - 2 Sept
Super 8 by Wyndham El Cajon/San Diego
SpringHill Suites by Marriott Chula Vista Eastlake
Outdoor pool

SpringHill Suites by Marriott Chula Vista Eastlake

3.5 star property
9.6 out of 10, Exceptional, (421)
"Nice pool and decent breakfast"
The price is €130
includes taxes & fees
7 Sept - 8 Sept
SpringHill Suites by Marriott Chula Vista Eastlake
Best Western Americana Inn
1 bedroom, pillow-top beds, in-room safe, desk

Best Western Americana Inn

2.5 star property
9.0 out of 10, Wonderful, (1141)
"Breakfast was amazing! "
The price is €120
includes taxes & fees
2 Sept - 3 Sept
Best Western Americana Inn
Valli Hi Motel
Desk, blackout curtains, soundproofing, free WiFi

Valli Hi Motel

2.5 star property
8.2 out of 10, Very good, (1009)
"Great hotel "
Valli Hi Motel
Hotel Palmeras Chula Vista
Front of property

Hotel Palmeras Chula Vista

2.0 star property
7.0 out of 10, Good, (1847)
"Great stay"
The price is €67
includes taxes & fees
28 Aug - 29 Aug
Hotel Palmeras Chula Vista
Best Western Chula Vista/Otay Valley Hotel
Lobby

Best Western Chula Vista/Otay Valley Hotel

2.5 star property
7.8 out of 10, Good, (1486)
"Clean, great staff. "
The price is €104
includes taxes & fees
3 Sept - 4 Sept
Best Western Chula Vista/Otay Valley Hotel
Best Western Plus Marina Gateway Hotel
Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed)

Best Western Plus Marina Gateway Hotel

3.5 star property
9.2 out of 10, Wonderful, (3242)
"Enjoyed my stay"
The price is €127
includes taxes & fees
7 Sept - 8 Sept
Best Western Plus Marina Gateway Hotel
Sea Harbor Hotel
Marina

Sea Harbor Hotel

2.0 star property
8.4 out of 10, Very good, (952)
"Good property for a few nights before your get on your boat for a fishing trip! "
The price is €178
includes taxes & fees
26 Sept - 27 Sept
Sea Harbor Hotel
Lamplighter Inn & Suites at SDSU
Outdoor pool, pool umbrellas, pool loungers

Lamplighter Inn & Suites at SDSU

2.5 star property
9.0 out of 10, Wonderful, (1245)
"We will definitely be staying there again"
The price is €131
includes taxes & fees
1 Sept - 2 Sept
Lamplighter Inn & Suites at SDSU
Loews Coronado Bay Resort
Exterior

Loews Coronado Bay Resort

4.0 star property
8.8 out of 10, Excellent, (1019)
"It was a lovely stay. "
The price is €229
includes taxes & fees
1 Sept - 2 Sept
Loews Coronado Bay Resort
Berkshire Motor Hotel
Suite | Private kitchenette

Berkshire Motor Hotel

2.5 star property
8.4 out of 10, Very good, (962)
"Great location within walking distance from the places we wanted to visit."
The price is €96
includes taxes & fees
7 Sept - 8 Sept
Berkshire Motor Hotel
Sentral Gaslamp Quarter
Premium bedding, pillow-top beds, desk, laptop workspace

Sentral Gaslamp Quarter

3.0 star property
9.2 out of 10, Wonderful, (318)
"Great place to stay!"
The price is €141
includes taxes & fees
28 Aug - 29 Aug
Sentral Gaslamp Quarter
Days Inn by Wyndham San Diego-East/El Cajon
Standard Room, 1 King Bed, Smoking

Days Inn by Wyndham San Diego-East/El Cajon

2.0 star property
7.6 out of 10, Good, (1009)
"Place was nice and comfy. Decent stay at a very genuine price. "
The price is €85
includes taxes & fees
2 Sept - 3 Sept
Days Inn by Wyndham San Diego-East/El Cajon
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa

Find the best Otay Mesa areas for the activities you enjoy most.

Downtown San Diego

2 out of top 10 points of interest in this area

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter featuring a city, signage and a bar

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Harlem of the West Sites – discover Gaslamp Quarter, a destination also famous for its shopping.

Belmont Park which includes rides and a garden

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Pacific Beach featuring a beach

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Crystal Pier while you're exploring the area.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach.

Top Otay Mesa Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Otay Mesa?

Otay Mesa is a neighbourhood that travellers like for its beaches, restaurants and shopping.

Where is the best hotel for a stay in Otay Mesa?

Based on Expedia customer reviews, Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is the highest ranked property in Otay Mesa. This hotel offers free breakfast and an outdoor pool. Another top choice in the area is Quality Suites San Diego Otay Mesa.

If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?

Yes! Most room reservations are refundable provided that you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Add dates, click "Search", then filter by "fully refundable" to view top deals in Otay Mesa.

What is there to do in this San Diego neighbourhood?

A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.