San Diego Hotel Guide. Hotels in Otay Mesa, San Diego, United States of America
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Our top choices for Otay Mesa hotels
Quality Suites San Diego Otay Mesa
Quality Suites San Diego Otay MesaOtay Mesa
7.2 out of 10, Good, (1,024 reviews)
"Very clean, bed was comfortable!"
Michael A
The price is €119
includes taxes & fees
2 Aug - 3 Aug
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHGOtay Mesa
8.2 out of 10, Very good, (1,775 reviews)
"Was happy with my stay! No complaints 👌"
Rafael
The price is €146
includes taxes & fees
12 Aug - 13 Aug
Valli Hi Motel
Valli Hi Motel7.9 km from Otay Mesa
8.4 out of 10, Very good, (1,057 reviews)
"It was a good stay."
AILEEN
The price is €90
includes taxes & fees
27 Jul - 28 Jul
Crowne Plaza San Diego - Mission Valley by IHG
Crowne Plaza San Diego - Mission Valley by IHG29.8 km from Otay Mesa
8.4 out of 10, Very good, (1,067 reviews)
"Really nice hotel "
sue
The price is €126
includes taxes & fees
29 Jul - 30 Jul
Best Western Americana Inn
Best Western Americana Inn8 km from Otay Mesa
8.8 out of 10, Excellent, (1,340 reviews)
"Clean room, ac was perfect staff was great"
Brandon
The price is €125
includes taxes & fees
2 Aug - 3 Aug
Sheraton San Diego Resort
Sheraton San Diego Resort28.1 km from Otay Mesa
8.4 out of 10, Very good, (3,572 reviews)
"Great stay"
Karen
The price is €231
includes taxes & fees
14 Aug - 15 Aug
Lafayette Hotel & Club
Lafayette Hotel & Club26.8 km from Otay Mesa
9.4 out of 10, Exceptional, (1,809 reviews)
"Great experience, staff was excellent food was delicious.. definitely recommend the hotel!"
Lisa
The price is €290
includes taxes & fees
21 Jul - 22 Jul
WoodSpring Suites Santee - San Diego Northeast
WoodSpring Suites Santee - San Diego Northeast30.9 km from Otay Mesa
8.4 out of 10, Very good, (158 reviews)
"Ashley, at the front desk was so happy and helpful!! Made my quick check in and shirt stay very easy!"
Cortney
The price is €115
includes taxes & fees
19 Jul - 20 Jul
Sycuan Casino Resort
Sycuan Casino Resort28.5 km from Otay Mesa
9.4 out of 10, Exceptional, (2,026 reviews)
"Exceptional hotel, staff and amenities. Love this hotel!"
CAROL
The price is €130
includes taxes & fees
5 Aug - 6 Aug
Carlton Oaks Lodge, an Ascend Collection Hotel
Carlton Oaks Lodge, an Ascend Collection Hotel31.6 km from Otay Mesa
8.2 out of 10, Very good, (1,004 reviews)
"Loved the restaurant!!"
Krista
The price is €128
includes taxes & fees
19 Jul - 20 Jul
La Quinta Inn by Wyndham San Diego Chula Vista
La Quinta Inn by Wyndham San Diego Chula Vista12.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,662 reviews)
"Very nice and clean hotel"
Lidia
The price is €127
includes taxes & fees
10 Aug - 11 Aug
Heritage Inn San Diego
Heritage Inn San Diego31.8 km from Otay Mesa
7.2 out of 10, Good, (1,672 reviews)
"Everyone was kind, rooms were great, AC worked perfectly, location was prime."
Scott
The price is €66
includes taxes & fees
10 Aug - 11 Aug
Hotel Palmeras Chula Vista
Hotel Palmeras Chula Vista14.4 km from Otay Mesa
7.2 out of 10, Good, (2,277 reviews)
"Excelente hotel"
ERICK GUADALUPE
The price is €73
includes taxes & fees
29 Jul - 30 Jul
Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway Hotel16.9 km from Otay Mesa
9.2 out of 10, Wonderful, (3,904 reviews)
"Nice location and clean hotel."
Abdelghani
The price is €182
includes taxes & fees
26 Jul - 27 Jul
Best Western Chula Vista/Otay Valley Hotel
Best Western Chula Vista/Otay Valley Hotel7.1 km from Otay Mesa
8.0 out of 10, Very good, (1,872 reviews)
"Nice right by the concert we were going to and staff was nice."
vanessa
The price is €122
includes taxes & fees
9 Aug - 10 Aug
Comfort Inn Chula Vista San Diego South
Comfort Inn Chula Vista San Diego South13 km from Otay Mesa
8.2 out of 10, Very good, (1,601 reviews)
"The room was comfortable and conveniently located. Breakfast was great for the cost of our stay."
Arsenia P
The price is €122
includes taxes & fees
9 Aug - 10 Aug
Hampton Inn & Suites San Diego Airport Liberty Station
Hampton Inn & Suites San Diego Airport Liberty Station29.2 km from Otay Mesa
9.2 out of 10, Wonderful, (1,731 reviews)
"As usual everything about our stay was great."
Edward
The price is €168
includes taxes & fees
3 Aug - 4 Aug
Ocean Villa Inn
Ocean Villa InnOcean Beach, 33.7 km from Otay Mesa
8.0 out of 10, Very good, (1,314 reviews)
"Very short walk to the beach, nice heated pool, really great breakfast spot attached! We loved our stay here and will be coming back!"
Hannah
The price is €190
includes taxes & fees
3 Aug - 4 Aug
Hotel Milagro
Hotel Milagro14.9 km from Otay Mesa
7.6 out of 10, Good, (1,000 reviews)
"Great hotel"
Mary
The price is €79
includes taxes & fees
27 Jul - 28 Jul
Motel 6 El Cajon, CA - San Diego
Motel 6 El Cajon, CA - San Diego27 km from Otay Mesa
7.4 out of 10, Good, (1,715 reviews)
"A good place to stay if you need a place to crash in for the night"
Ivy Ruth
The price is €83
includes taxes & fees
16 Jul - 17 Jul
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Otay Mesa
Find the best Otay Mesa areas for the activities you enjoy most.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Seaport Village are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Pacific Beach
Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.
Mission Beach
If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.
Gaslamp Quarter
San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.
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