What is Santo Domingo like?

Travellers to Mexico City's Santo Domingo neighbourhood will be sure to enjoy a stay here.

How many hotels will I find in the Santo Domingo area?

Book one of Expedia's 6 hotels and other accommodation options in Santo Domingo and start exploring everything Mexico City has to offer.

If I need to cancel my hotel reservation in Santo Domingo, will I receive a refund?

Yes, most room reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to review the best deals available in Santo Domingo.

What are the top things to see and do in Santo Domingo?

Estadio Azteca, Centro Cultural y Social Veracruzano and Teatro Rafael Solana are just a few of the places to visit in and around Santo Domingo. While you're out sightseeing, Parroquia de San Juan Bautista and Casa del Teatro are a couple of additional sights to visit in Mexico City.

Santo Domingo hotels, Mexico City, Mexico: Mexico City Hotel Guide

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for Santo Domingo hotels

1. UNAM CIUDAD DE MEXICO CASA DE HUESPEDES

Santo Domingo

includes taxes & fees

24 Sept - 25 Sept

2. Fiesta Inn Periferico Sur

Coyoacan, 2.9 km from Santo Domingo

Rafael

includes taxes & fees

20 Sept - 21 Sept

3. Radisson Paraiso Hotel Mexico City

Tlalpan, 3.9 km from Santo Domingo

Alma Maria Valerio

includes taxes & fees

14 Sept - 15 Sept

4. Krystal Grand Suites Insurgentes

3.4 km from Santo Domingo

Jorge

includes taxes & fees

26 Sept - 27 Sept

5. Hacienda Peña Pobre

Tlalpan, 4.4 km from Santo Domingo

jorge genaro

includes taxes & fees

13 Sept - 14 Sept

6. Royal Pedregal Hotel

Tlalpan, 4.6 km from Santo Domingo

Luis Fernando

includes taxes & fees

19 Sept - 20 Sept

7. Galeria Plaza San Jeronimo

5.1 km from Santo Domingo

Steven

includes taxes & fees

13 Sept - 14 Sept

8. Hotel Amala

7.6 km from Santo Domingo

Michel

includes taxes & fees

13 Oct - 14 Oct

9. Econo Express Hotel by Nokte Inn

Benito Juarez, 6.4 km from Santo Domingo

Rosario

includes taxes & fees

27 Sept - 28 Sept

10. Camino Real Pedregal Mexico

6.1 km from Santo Domingo

Bruno

includes taxes & fees

26 Sept - 27 Sept

11. El Diplomatico Hotel

Benito Juarez, 5.9 km from Santo Domingo

Paul

includes taxes & fees

13 Sept - 14 Sept

12. Fiesta Inn Insurgentes Sur

4.4 km from Santo Domingo

Luis Miguel

includes taxes & fees

18 Sept - 19 Sept

13. WeEnjoy Hotels Aeropuerto CDMX

10.8 km from Santo Domingo

HECTOR

includes taxes & fees

13 Sept - 14 Sept

14. Holiday Inn Mexico Dali Airport by IHG

Venustiano Carranza, 9.9 km from Santo Domingo

Helen

includes taxes & fees

16 Sept - 17 Sept

15. Holiday Inn Express Mexico Aeropuerto by IHG

10.6 km from Santo Domingo

Mehran

includes taxes & fees

12 Oct - 13 Oct

16. Hotel Harare

Benito Juarez, 7.1 km from Santo Domingo

erika

includes taxes & fees

20 Sept - 21 Sept

17. Krystal Urban Aeropuerto Cd de Mexico

11.2 km from Santo Domingo

Bruce

includes taxes & fees

10 Oct - 11 Oct

18. Hotel Escala Siglo XXI

Cuauhtémoc, 9.4 km from Santo Domingo

Roberto

includes taxes & fees

17 Sept - 18 Sept

19. Fiesta Americana Viaducto Aeropuerto

10.3 km from Santo Domingo

Chelsea

includes taxes & fees

4 Oct - 5 Oct

20. Hotel Riazor Aeropuerto

9.8 km from Santo Domingo

Sergio

includes taxes & fees

17 Sept - 18 Sept

View all properties

Where to stay in Santo Domingo

Find the best Santo Domingo areas for the activities you enjoy most.

An aerial view of a city with a central circular plaza, surrounded by buildings and trees.

Roma Norte

Known for its fascinating museums and popular shops, there's plenty to explore in Roma Norte. Check out top attractions like Avenida Insurgentes and MUCA Roma, and jump on the metro at Insurgentes Station or Sevilla Station to see more of the city.

See properties

A stone monument with inscriptions, surrounded by lush greenery and a clear sky.

Polanco

Visit the most diverse section of Mexico City for sophisticated shopping, dining, accommodations and sightseeing.

See properties

A row of colorful buildings with balconies and ornate doors.

La Condesa

Enjoy 20th-century history in these two sections of Mexico City, with interesting art and architecture reflecting European influences.

See properties

A grand building with a large golden dome and classical architecture.

Historic Center

Consider a visit to Zócalo and take some time to enjoy the interesting museums during your time in Historic Center. If you want to see more of the city, jump on the metro at Allende Station or Bellas Artes Station.

See properties

A city street at dusk with illuminated buildings, palm trees, and vehicles with light trails.

Reforma

Consider a visit to Angel of Independence Monument and take some time to enjoy the important monuments during your time in Reforma. If you want to see more of the city, jump on the metro at Insurgentes Station or Cuauhtemoc Station.

See properties