Photo by JG Morris

Southeast Missouri Hotel Guide - Casino Hotels in Southeast Missouri, Missouri
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check availability on Southeast Missouri Casino Hotels
Our top choices for Southeast Missouri hotels with a casino

1. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
8.8 out of 10, Excellent, (897 reviews)
The price is €78
includes taxes & fees
22 Nov - 23 Nov

2. The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (705 reviews)
The price is €117
includes taxes & fees
15 Nov - 16 Nov

3. The Farmstead Hotel
The Farmstead HotelCaruthersville
8.6 out of 10, Excellent, (628 reviews)
The price is €98
includes taxes & fees
15 Nov - 16 Nov

4. Century Casino & Hotel Caruthersville
Century Casino & Hotel CaruthersvilleCaruthersville
8.6 out of 10, Excellent, (205 reviews)
The price is €125
includes taxes & fees
15 Nov - 16 Nov

5. Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (562 reviews)
The price is €119
includes taxes & fees
29 Nov - 30 Nov

6. Baymont by Wyndham Festus
Baymont by Wyndham FestusFestus
6.8 out of 10, (1,000 reviews)
The price is €64
includes taxes & fees
14 Dec - 15 Dec

7. Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly
Romantic Creekside Retreat | Fireplace | Deck | Pet FriendlyCape Girardeau
10.0 out of 10, Exceptional, (3 reviews)
The price is €200
includes taxes & fees
18 Nov - 19 Nov

8. Enchanted Mermaid A-Frame | Creek + Fire pit | Pet Friendly
Enchanted Mermaid A-Frame | Creek + Fire pit | Pet FriendlyCape Girardeau
10.0 out of 10, Exceptional, (1 review)
The price is €202
includes taxes & fees
20 Nov - 21 Nov

9. Purple Tiny House with Fire pit & Nature
Purple Tiny House with Fire pit & NatureCape Girardeau
10.0 out of 10, Exceptional, (1 review)
The price is €183
includes taxes & fees
15 Nov - 16 Nov

10. The Little Cape Lofted Cottage | Creek & Nature
The Little Cape Lofted Cottage | Creek & NatureCape Girardeau
9.0 out of 10, Wonderful, (2 reviews)
The price is €207
includes taxes & fees
2 Dec - 3 Dec
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Southeast Missouri Hotel Reviews

Pear Tree Inn Cape Girardeau West
10/10 Excellent

Drury Inn & Suites Hayti Caruthersville
10/10 Excellent
Explore a world of travel with Expedia
- Allenville Hotels
- Arcadia Hotels
- Belleview Hotels
- Bernie Hotels
- Black Hotels
- Bloomsdale Hotels
- Bonne Terre Hotels
- Broseley Hotels
- Bunker Hotels
- Caledonia Hotels
- Cape Girardeau Hotels
- Cherryville Hotels
- Clearwater Hotels
- Desloge Hotels
- St. Francois County Hotels
- Hotels with Pool in Dexter
- Dexter Hotels
- Wyndham Hotels in Doe Run
- Hotels near eDen Spa & Salon
- Ellington Hotels
- Eminence Hotels
- Fredericktown Hotels
- Fruitland Hotels
- Gordonville Hotels
- Historic Hotels in Ironton
- Ironton Hotels
- Lesterville Hotels
- Marble Hill Hotels
- Cabin Rentals in Middle Brook
- Hilton Hotels in Middle Brook
- Hotels near National Shrine of Our Lady of the Miraculous Medal
- Perryville Hotels
- Poplar Bluff Hotels
- Qulin Hotels
- Sikeston Hotels
- Motel 6 Hotels in Southeast Missouri
- Hotels near Southeast Missouri State University
- B&B in St Mary
- Ste Genevieve Hotels
- Aimbridge Hospitality Hotels in Tiff
- Tiff Hotels
- Hotels near Trail of Tears State Park
- Van Buren Hotels
- Arcadia Holidays
- Visit Bernie
- Visit Bloomsdale
- Visit Bonne Terre
- Cave Spring Park
- Dexter Holidays
- Visit Doniphan
- Eden Spa & Salon
- Visit Fredericktown
- Visit Grandin
- Johnson's Shut-ins State Park
- K Bridge Recreation Area
- Visit Old Appleton
- Visit Ozora
- Visit Park Hills
- Visit Qulin
- Rocky Falls
- Van Buren Holidays
- Visit Van Buren
- Walnut Hollow Lake
- Visit Wappapello
- Washington State Park
- Ace New Zealand Rental Cars in Doe Run
- Ada Rental Cars in New Offenburg
- Addcar rental Rental Cars in Fruitland
- Apex Car Rentals Rental Cars in Southeast Missouri
- Auto Rent Rental Cars in Black
- Car hire Black
- Goldcar Key’n Go Rental Cars in Cherryville
- Island Car Rentals Rental Cars in Ellington
- Ok Mobility Rental Cars in Grandin
- Priceless Car Rental Rental Cars in Black
- Sicily By Car Rental Cars in Delta





























