Photo by JG Morris

Southeast Missouri Hotel Guide - Family Friendly Hotels in Southeast Missouri, Missouri
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Our top choices for Southeast Missouri family-friendly hotels

1. Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,002 reviews)
The price is €76
includes taxes & fees
22 Nov - 23 Nov

2. Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,004 reviews)
The price is €101
includes taxes & fees
13 Nov - 14 Nov

3. Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (977 reviews)
The price is €98
includes taxes & fees
15 Nov - 16 Nov

4. Hampton Inn Poplar Bluff
Hampton Inn Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (1,015 reviews)
The price is €90
includes taxes & fees
6 Dec - 7 Dec

5. Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (200 reviews)
The price is €87
includes taxes & fees
15 Nov - 16 Nov

6. EC Reed's Mercantile and Hotel
EC Reed's Mercantile and HotelMarble Hill
9.4 out of 10, Exceptional, (118 reviews)
The price is €103
includes taxes & fees
15 Nov - 16 Nov

7. Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.2 out of 10, Wonderful, (1,001 reviews)
The price is €73
includes taxes & fees
15 Nov - 16 Nov

8. The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (702 reviews)
The price is €116
includes taxes & fees
12 Nov - 13 Nov

9. Hampton Inn By Hilton Dexter
Hampton Inn By Hilton DexterDexter
9.6 out of 10, Exceptional, (83 reviews)
The price is €99
includes taxes & fees
15 Nov - 16 Nov

10. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
8.8 out of 10, Excellent, (895 reviews)
The price is €78
includes taxes & fees
12 Nov - 13 Nov

11. Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,002 reviews)
The price is €97
includes taxes & fees
15 Nov - 16 Nov

12. Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (242 reviews)
The price is €102
includes taxes & fees
15 Nov - 16 Nov

13. Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (559 reviews)
The price is €118
includes taxes & fees
19 Nov - 20 Nov

14. Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 EastCape Girardeau
9.6 out of 10, Exceptional, (860 reviews)
The price is €99
includes taxes & fees
15 Nov - 16 Nov

15. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,001 reviews)
The price is €101
includes taxes & fees
7 Dec - 8 Dec

16. Shepherd Mountain Inn
Shepherd Mountain InnIronton
9.2 out of 10, Wonderful, (338 reviews)
The price is €121
includes taxes & fees
10 Nov - 11 Nov

17. Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
10.0 out of 10, Exceptional, (119 reviews)
The price is €130
includes taxes & fees
8 Dec - 9 Dec

18. TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott SikestonSikeston
9.2 out of 10, Wonderful, (31 reviews)
The price is €108
includes taxes & fees
15 Nov - 16 Nov

19. Hampton Inn & Suites By Hilton Festus
Hampton Inn & Suites By Hilton FestusFestus
9.4 out of 10, Exceptional, (26 reviews)
The price is €117
includes taxes & fees
22 Nov - 23 Nov

20. Holiday Inn Poplar Bluff by IHG
Holiday Inn Poplar Bluff by IHGPoplar Bluff
8.8 out of 10, Excellent, (806 reviews)
The price is €81
includes taxes & fees
15 Nov - 16 Nov
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family-friendly hotels with free breakfast in Southeast Missouri

9.2 out of 10, Wonderful, (338)
The price is €121
includes taxes & fees
10 Nov - 11 Nov
Family-friendly hotels with pools in Southeast Missouri

9.4 out of 10, Exceptional, (1001)
The price is €91
includes taxes & fees
15 Nov - 16 Nov
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Southeast Missouri Hotel Reviews

Comfort Inn Festus - St Louis South
8/10 Good
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