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Southeast Missouri Hotel Guide - Family Friendly Hotels in Southeast Missouri, Missouri

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Check availability on Southeast Missouri Family Friendly Hotels

Tonight
24 Sept - 25 Sept
Tomorrow
25 Sept - 26 Sept
This weekend
25 Sept - 27 Sept
Next weekend
2 Oct - 4 Oct

Our top choices for Southeast Missouri family-friendly hotels

A modern kitchen with a coffee machine, a refrigerator, and a microwave.
A long, narrow hallway with patterned carpet, doors on both sides, and a ceiling light.
A bathroom with a white toilet, a bathtub, and a shower curtain.
A laundry room with a front-loading washer and dryer, a door, and a light fixture.

1. Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington
Farmington
€57
includes taxes & fees
11 Oct - 12 Oct
Super 8 by Wyndham Farmington
A narrow corridor with a bar area on the right, featuring a counter and hanging lights.
A large boulder in a natural setting with autumn-colored trees in the background.
A bathroom with a shower area, a tiled floor, and a sink with toiletries.

2. Black River Motel and Restaurant

Black River Motel and Restaurant
Lesterville
€107
includes taxes & fees
28 Sept - 29 Sept
Black River Motel and Restaurant
A dining area with tables and chairs, a kitchen area, and a TV mounted on the wall.
A hotel reception area with a glass partition, a reception desk, and a digital kiosk.
A parking lot with a tree in bloom, a red fire hydrant, and a building in the background.
A gym with cardio equipment, a bench press, and a squat rack.

3. Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
Farmington
  • Seasonal outdoor pool and family-friendly perks create magical memories at this Farmington retreat just minutes from adventure.
€54
includes taxes & fees
25 Oct - 26 Oct
Baymont Inn and Suites by Wyndham Farmington, MO
An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.
A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.
A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.
A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.

4. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
Sikeston
  • Children's paradise awaits with splash-worthy indoor and outdoor pools, free breakfast buffet, and family-focused amenities all day long.
€107
includes taxes & fees
29 Sept - 30 Sept
Drury Inn & Suites Sikeston, MO
A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.
An outdoor patio with tables and chairs, a stone wall, and large windows.
A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.
A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

5. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Jackson
  • Family getaway with indoor pool and kid-friendly perks near Cape Splash Family Aquatic Centre.
€80
includes taxes & fees
27 Sept - 28 Sept
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.
A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

6. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
  • A family paradise with splash-worthy fun awaits, where complimentary breakfast and an indoor pool create lasting memories for all ages.
€99
includes taxes & fees
28 Sept - 29 Sept
Drury Plaza Hotel Cape Girardeau Conference Center
A hotel room with a bed, a sofa, a desk, and a chair.
A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.
A modern living room with a sofa, armchairs, a coffee table, and a painting on the wall.
An indoor swimming pool with a tiled edge, surrounded by lounge chairs and potted plants.

7. Holiday Inn Express & Suites Farmington by IHG

Holiday Inn Express & Suites Farmington by IHG
Farmington
  • Family fun destination with an indoor pool and fitness centre, plus a delicious free breakfast every morning.
€112
includes taxes & fees
4 Oct - 5 Oct
Holiday Inn Express & Suites Farmington by IHG
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.
A hotel room with two beds, a desk, and a chair.
A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.
A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

8. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
€100
includes taxes & fees
1 Oct - 2 Oct
Fairfield Inn & Suites by Marriott Cape Girardeau
A hotel room with a large bed, two bedside tables, a nightstand, and a framed picture on the wall.
A modern kitchen with granite countertops, wooden chairs, and a dining table. There are various food items and a sign indicating hot beverages.
A hotel reception area with a green carpet, a reception desk, a seating area with chairs, and a poster advertising the hotel.
An indoor swimming pool with clear lanes, a sunlit room with a view, and a staircase leading to an upper level.

9. Quality Inn Farmington

Quality Inn Farmington
Farmington
  • Adventure awaits with a family-friendly indoor pool and free extras just minutes from St. Joe State Park.
€57
includes taxes & fees
18 Oct - 19 Oct
Quality Inn Farmington
A reception desk with a sign reading 'Deerfield Inn & Suites' and a welcome sign.
A hotel lobby with a reception desk, a dining area with chairs and a table, a clock on the wall, and an exit sign.
A bathroom with a bathtub, toilet, and a towel rack.

10. Deerfield Inn & Suites Steele Near Blytheville I 55

Deerfield Inn & Suites Steele Near Blytheville I 55
Steele
€56
includes taxes & fees
25 Sept - 26 Sept
Deerfield Inn & Suites Steele Near Blytheville I 55
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Choose what matters most at family-friendly hotels in Southeast Missouri

Breakfast included
Pool
All-inclusive
4 stars
5 stars

Family-friendly hotels with free breakfast in Southeast Missouri

A modern kitchen with a coffee machine, a refrigerator, and a microwave.
A hotel room with a large bed, a smaller bed, a nightstand with a lamp, and two large framed pictures on the wall.
A long, narrow hallway with patterned carpet, doors on both sides, and a ceiling light.
A laundry room with a front-loading washer and dryer, a door, and a light fixture.

Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington
Farmington
€57
includes taxes & fees
11 Oct - 12 Oct
Super 8 by Wyndham Farmington
A dining area with tables and chairs, a kitchen area, and a TV mounted on the wall.
A hotel reception area with a glass partition, a reception desk, and a digital kiosk.
A parking lot with a tree in bloom, a red fire hydrant, and a building in the background.
A gym with cardio equipment, a bench press, and a squat rack.

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
Farmington
€54
includes taxes & fees
25 Oct - 26 Oct
Baymont Inn and Suites by Wyndham Farmington, MO
An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.
A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.
A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.
A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
Sikeston
€107
includes taxes & fees
29 Sept - 30 Sept
Drury Inn & Suites Sikeston, MO
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.
An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.
A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.
A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
€100
includes taxes & fees
1 Oct - 2 Oct
Fairfield Inn & Suites by Marriott Cape Girardeau
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.
A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
€99
includes taxes & fees
28 Sept - 29 Sept
Drury Plaza Hotel Cape Girardeau Conference Center
A hotel room with a large bed, a nightstand, a lamp, a chair, and a mirror.
A conference room with tables and chairs, framed artwork on the walls, and a carpeted floor.
A kitchen counter with a coffee machine, a kettle, and storage boxes.
A modern dining area with high tables and chairs, a television screen, and a view of the outdoors through large windows.

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
Perryville
€105
includes taxes & fees
4 Oct - 5 Oct
Holiday Inn Express & Suites Perryville by IHG
A hotel room with a large bed, two bedside tables, a nightstand, and a framed picture on the wall.
A hotel reception area with a green carpet, a reception desk, a seating area with chairs, and a poster advertising the hotel.
A modern waiting area with a grey sofa, a small table, and a black office chair. There are two doors with signs indicating restrooms.
An indoor swimming pool with clear lanes, a sunlit room with a view, and a staircase leading to an upper level.

Quality Inn Farmington

Quality Inn Farmington
Farmington
€57
includes taxes & fees
18 Oct - 19 Oct
Quality Inn Farmington
A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.
An outdoor patio with tables and chairs, a stone wall, and large windows.
A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.
A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Jackson
€80
includes taxes & fees
27 Sept - 28 Sept
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
An indoor swimming pool with clear water, surrounded by lounge chairs and a tiled floor.
A hotel room with two beds, a flat-screen TV, a desk, and a window with blinds.
A modern hotel lobby with multiple seating areas, a large flat-screen TV mounted on the wall, and a visible exit sign.
A hotel room with a wooden desk, a chair, a television, a microwave, and a minibar.

Hampton Inn Farmington

Hampton Inn Farmington
Farmington
€108
includes taxes & fees
4 Oct - 5 Oct
Hampton Inn Farmington
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.
A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.
A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
€71
includes taxes & fees
4 Oct - 5 Oct
Pear Tree Inn Cape Girardeau West
View all properties

Family-friendly hotels with pools in Southeast Missouri

A dining area with tables and chairs, a kitchen area, and a TV mounted on the wall.
A hotel reception area with a glass partition, a reception desk, and a digital kiosk.
A parking lot with a tree in bloom, a red fire hydrant, and a building in the background.
A gym with cardio equipment, a bench press, and a squat rack.

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
Farmington
€54
includes taxes & fees
25 Oct - 26 Oct
Baymont Inn and Suites by Wyndham Farmington, MO
A modern kitchen with a coffee machine, a refrigerator, and a microwave.
A hotel room with a large bed, a smaller bed, a nightstand with a lamp, and two large framed pictures on the wall.
A long, narrow hallway with patterned carpet, doors on both sides, and a ceiling light.
A laundry room with a front-loading washer and dryer, a door, and a light fixture.

Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington
Farmington
€57
includes taxes & fees
11 Oct - 12 Oct
Super 8 by Wyndham Farmington
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.
A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
€99
includes taxes & fees
28 Sept - 29 Sept
Drury Plaza Hotel Cape Girardeau Conference Center
A spacious lobby with a reception desk, seating area, and large windows.
A hotel room with a bed, a desk, a chair, a sofa, and a TV.
A spacious lobby with a high ceiling, a mezzanine level, and a seating area with a sofa and chairs.
An indoor swimming pool with a clear view of the outside through large windows.

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
Poplar Bluff
€96
includes taxes & fees
18 Oct - 19 Oct
Drury Inn & Suites Poplar Bluff
A hotel room with a large bed, two bedside tables, a nightstand, and a framed picture on the wall.
A hotel reception area with a green carpet, a reception desk, a seating area with chairs, and a poster advertising the hotel.
A modern waiting area with a grey sofa, a small table, and a black office chair. There are two doors with signs indicating restrooms.
An indoor swimming pool with clear lanes, a sunlit room with a view, and a staircase leading to an upper level.

Quality Inn Farmington

Quality Inn Farmington
Farmington
€57
includes taxes & fees
18 Oct - 19 Oct
Quality Inn Farmington
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.
An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.
A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.
A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
€100
includes taxes & fees
1 Oct - 2 Oct
Fairfield Inn & Suites by Marriott Cape Girardeau
A hotel room with a bed, a sofa, a desk, and a chair.
A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.
A modern living room with a sofa, armchairs, a coffee table, and a painting on the wall.
An indoor swimming pool with a tiled edge, surrounded by lounge chairs and potted plants.

Holiday Inn Express & Suites Farmington by IHG

Holiday Inn Express & Suites Farmington by IHG
Farmington
€112
includes taxes & fees
4 Oct - 5 Oct
Holiday Inn Express & Suites Farmington by IHG
A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.
An outdoor patio with tables and chairs, a stone wall, and large windows.
A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.
A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Jackson
€80
includes taxes & fees
27 Sept - 28 Sept
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
An indoor swimming pool with clear water, surrounded by lounge chairs and a tiled floor.
A hotel room with two beds, a flat-screen TV, a desk, and a window with blinds.
A modern hotel lobby with multiple seating areas, a large flat-screen TV mounted on the wall, and a visible exit sign.
A hotel room with a wooden desk, a chair, a television, a microwave, and a minibar.

Hampton Inn Farmington

Hampton Inn Farmington
Farmington
€108
includes taxes & fees
4 Oct - 5 Oct
Hampton Inn Farmington
A table with two chairs under a large tree with a potted plant on it.
A modern living room with a sofa, coffee table, and a ladder against the wall.
A red telephone booth with a crown emblem, a wooden shelf with jars, and a wicker chair.
A restaurant interior with wooden tables and chairs, green cushioned benches, and a ceiling adorned with hanging plants and lights.

Pickleball Cafe & Micro Hotel

Pickleball Cafe & Micro Hotel
Ironton
€203
includes taxes & fees
27 Sept - 28 Sept
Pickleball Cafe & Micro Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southeast Missouri Hotel Reviews

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

10/10 Excellent
"Perfect Stay. Friendly Staff. Conveniently Located. Comfortable Bed. Nice Hot Shower. Ice Cold Shower."
Ronald 3-night trip
Posted 12 hours ago
Baymont Inn and Suites by Wyndham Farmington, MO
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"Clean room and perfect stay. We have come to consistently appreciate Drury brand for a quality stay. We would definitely recommend this location for clean comfortable accommodations."
Hiram 1-night trip
Posted 22 hours ago
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

10/10 Excellent
"Clean room, staff"
Lavonne 2-night trip
Posted 1 day ago
Drury Inn & Suites Poplar Bluff
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

10/10 Excellent
"Easy checkin, clean facilities, safe area. Quiet with a comfy bed."
Deandra 1-night trip
Posted 2 days ago
Motel 6 Poplar Bluff, MO
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent
"This was a very good value. It has been the best hotel I've stayed at in awhile."
David 1-night trip
Posted 3 days ago
Days Inn and Suites by Wyndham Sikeston
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

8/10 Good
"I was looking for something that was good quality and wouldn’t break my wallet. This place was what I was expecting. Lady working the breakfast was extremely polite and helpful."
Jennifer 1-night trip
Posted 4 days ago
Pear Tree Inn Cape Girardeau West

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