Photo by Bill Dillard

Southeast Missouri Hotel Guide - Hotels with Spa in Southeast Missouri, Missouri

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southeast Missouri Hotels with Spa

Tonight
24 Nov - 25 Nov
Tomorrow
25 Nov - 26 Nov
This weekend
28 Nov - 30 Nov
Next weekend
5 Dec - 7 Dec

Top Southeast Missouri Hotels with Spa

Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1002)
"It was right off the interstate with lots of restaurant options "
United States
Kelly
The price is €93
includes taxes & fees
26 Nov - 27 Nov
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Southeast Missouri Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"Breakfast and super Kickoff was AWESOME? love this hotel!!!"
Dorothy 2-night trip
Posted 22 hours ago
Drury Plaza Hotel Cape Girardeau Conference Center

Explore a world of travel with Expedia