Lodging Image

Holiday Homes in Southeast Missouri

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
4 Sept - 6 Sept
In two months
16 Oct - 18 Oct
In three months
13 Nov - 15 Nov
In four months
11 Dec - 13 Dec

Our top choices for Southeast Missouri holiday homes

A porch with four green Adirondack chairs, a small table, and string lights.

1. *State Parks*Bungalow*CoffeeBar*Pet Friendly*Porch

*State Parks*Bungalow*CoffeeBar*Pet Friendly*Porch
Ironton
10.0 out of 10, Exceptional, (39 reviews)
"Great place to stay!"
United States
Derek R.
The price is €235
includes taxes & fees
24 Aug - 25 Aug
*State Parks*Bungalow*CoffeeBar*Pet Friendly*Porch
A bedroom with a bed, a bench, and a ceiling fan.

2. AV Bungalows #9B

AV Bungalows #9B
Arcadia
10.0 out of 10, Exceptional, (2 reviews)
"My husband and I really enjoyed our stay! The Bungalow was perfect for us and will definitely be staying again when we come back to Arcadia!!"
United States
Theresa R.
The price is €147
includes taxes & fees
31 Aug - 1 Sept
AV Bungalows #9B
A modern kitchen with grey cabinets, a black refrigerator, and a microwave.

3. "The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington

"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington
Farmington
10.0 out of 10, Exceptional, (26 reviews)
"Very nice stay we enjoyed would definitely stay again"
United States
Ben C.
The price is €211
includes taxes & fees
3 Sept - 4 Sept
"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington
A wooden deck with outdoor seating and a fire pit, surrounded by trees.

4. The Stonehouse - Private Hot Tub - Sleeps 5

The Stonehouse - Private Hot Tub - Sleeps 5
Fredericktown
9.8 out of 10, Exceptional, (7 reviews)
"The Stonehouse was every bit as cute and comfortable as expected! We enjoyed staying here as a great base for hiking in the area. The tiny town is a neat complex of different types of place to stay plus the Station coffee house was great to have in walking distance. "
United States
Beth A.
The price is €210
includes taxes & fees
23 Aug - 24 Aug
The Stonehouse - Private Hot Tub - Sleeps 5
A wooden dining table with two wine glasses and a basket containing a bottle of champagne, snacks, and a bottle of Welch's.

5. Cozy 1-bedroom house with AC and WiFi in charming Farmington

Cozy 1-bedroom house with AC and WiFi in charming Farmington
Farmington
10.0 out of 10, Exceptional, (15 reviews)
"Beautiful and perfect for travelers!!!!!"
United States
Elizabeth
The price is €169
includes taxes & fees
3 Sept - 4 Sept
Cozy 1-bedroom house with AC and WiFi in charming Farmington
A kitchen with white cabinets, a wooden dining table, a built-in stove, and a trash can.

6. Cozy Three bedroom home in Central Farmington

Cozy Three bedroom home in Central Farmington
Farmington
9.8 out of 10, Exceptional, (34 reviews)
"Great little house and was perfect for our weekend trip to Farmington! Would recommend."
United States
Daniel K.
The price is €219
includes taxes & fees
3 Sept - 4 Sept
Cozy Three bedroom home in Central Farmington
A window with a vase of flowers and a book on a wooden table.

7. The Sutton House 2 blocks from Main Street & Courthouse Square

The Sutton House 2 blocks from Main Street & Courthouse Square
Ironton
10.0 out of 10, Exceptional, (63 reviews)
"We enjoyed our stay. Nice big comfortable beds. Short walk to coffee shop & short drive to several nice hiking spots. "
United States
Nicole K.
The price is €209
includes taxes & fees
22 Sept - 23 Sept
The Sutton House 2 blocks from Main Street & Courthouse Square
A wooden deck with two Adirondack chairs and a hammock.

8. Tiny Houses of French Village

Tiny Houses of French Village
2.5 star property
French Village
10.0 out of 10, Exceptional, (6 reviews)
"Very nice place very clean well kept inside an out it's a nice little romantic getaway they have it set up so great its a must see sunset very relaxing "
United States
Chris
The price is €264
includes taxes & fees
24 Aug - 25 Aug
Tiny Houses of French Village
A wooden deck with steps leading to a house, surrounded by trees.

9. Get Away Acres 1/2 mile off highway 60 extra sanitized

Get Away Acres 1/2 mile off highway 60 extra sanitized
Ellsinore
10.0 out of 10, Exceptional, (99 reviews)
"Gorgeous property, wonderful hosts. Would love to visit again "
United States
Anonymous traveller
The price is €116
includes taxes & fees
26 Aug - 27 Aug
Get Away Acres 1/2 mile off highway 60 extra sanitized
A modern kitchen with white cabinets, a stainless steel microwave, and a coffee bar with stools.

10. Charming 1860s Renovated Home

Charming 1860s Renovated Home
Ironton
8.0 out of 10, Very good, (20 reviews)
"Had a great stay"
United States
Kevin S.
The price is €230
includes taxes & fees
11 Sept - 12 Sept
Charming 1860s Renovated Home
A house with a porch, a staircase, and a door.

11. "The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC

"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC
Farmington
10.0 out of 10, Exceptional, (11 reviews)
"Thank you again for a great stay! This is a perfect little cabin !"
United States
Angela S.
The price is €211
includes taxes & fees
3 Sept - 4 Sept
"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC
A person sitting on rocks by a flowing river surrounded by greenery.

12. Your home away from home in downtown, historic Farmington!

Your home away from home in downtown, historic Farmington!
Farmington
10.0 out of 10, Exceptional, (50 reviews)
"We loved the location and the charm. And the chickens and friendly kitty were a bonus. Great stay. "
United States
Jenny R.
The price is €213
includes taxes & fees
3 Sept - 4 Sept
Your home away from home in downtown, historic Farmington!
A covered outdoor seating area with a table and chairs, string lights, and a gravel ground.

13. Clifford's Country Cottage

Clifford's Country Cottage
Bonne Terre
10.0 out of 10, Exceptional, (41 reviews)
"Great stay, very clean and comfortable."
United States
Chris G.
The price is €134
includes taxes & fees
23 Aug - 24 Aug
Clifford's Country Cottage
A compact living space with a sofa, dining table, kitchen area, and a ceiling fan.

14. Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations

Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations
Farmington
9.0 out of 10, Wonderful, (7 reviews)
"Host was very helpful and accommodating! Very cute and small house, perfect for our weekend stay! "
United States
Amber P.
The price is €131
includes taxes & fees
3 Sept - 4 Sept
Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations

15. The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO

The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO
Dexter
The price is €135
includes taxes & fees
6 Sept - 7 Sept
The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO
A campfire surrounded by benches in a wooded park area.

16. Brown's Lake House, Family-Friendly 2 Bedroom Retreat Near Lake Wappapello

Brown's Lake House, Family-Friendly 2 Bedroom Retreat Near Lake Wappapello
Wappapello
10.0 out of 10, Exceptional, (1 review)
"Very cozy"
United States
Shea E.
The price is €232
includes taxes & fees
24 Aug - 25 Aug
Brown's Lake House, Family-Friendly 2 Bedroom Retreat Near Lake Wappapello
A red barn with a sloped roof, surrounded by a grassy field and trees.

17. The Weber Farm - Enjoy a beautiful 100 acre farm!

The Weber Farm - Enjoy a beautiful 100 acre farm!
Frohna
10.0 out of 10, Exceptional, (34 reviews)
"Wonderful time! "
United States
Alison C.
The Weber Farm - Enjoy a beautiful 100 acre farm!
A fire pit table with four Adirondack chairs around it, set on a concrete patio with a grassy field in the background.

18. King Bed, game room minutes from downtown, golf courses + BIG back yard sleeps 8

King Bed, game room minutes from downtown, golf courses + BIG back yard sleeps 8
Farmington
10.0 out of 10, Exceptional, (33 reviews)
"Awesome place to stay and great host!"
United States
Mike M.
The price is €280
includes taxes & fees
24 Aug - 25 Aug
King Bed, game room minutes from downtown, golf courses + BIG back yard sleeps 8
A living room with a TV, a fireplace, a sofa, and wall art.

19. Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.4 out of 10, Very good, (57 reviews)
"Great cute place. "
United States
Jeremy W.
The price is €97
includes taxes & fees
23 Aug - 24 Aug
Little Blue Cottage on Spanish
A two-story cylindrical building with a covered porch and a welcoming sign.

20. Silo Farm Haus- located in the heart of wine country!

Silo Farm Haus- located in the heart of wine country!
Ste. Genevieve
10.0 out of 10, Exceptional, (154 reviews)
"We had an amazing time! Great property and cozy. We had a few dead flies in the bed but otherwise perfect stay!"
United States
Anthony S.
The price is €321
includes taxes & fees
23 Aug - 24 Aug
Silo Farm Haus- located in the heart of wine country!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Southeast Missouri Hotel Reviews

The Riverview

The Riverview

10/10 Excellent
"Very clean rooms, nice hotel."
Alyssa 1-night trip
Posted 2 hours ago
The Riverview

Find out more about Southeast Missouri

Southeast Missouri Holiday Homes information

Number of reviews
664
Accommodation
207 Holiday Homes
Lowest Price
€97
Highest Price
€321

Explore a world of travel with Expedia