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Southern Illinois Hotel Guide - Hotels with Spa in Southern Illinois, Illinois

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Check availability on Southern Illinois Hotels with Spa

Tonight
6 Sept - 7 Sept
Tomorrow
7 Sept - 8 Sept
Next weekend
11 Sept - 13 Sept
In two weeks
18 Sept - 20 Sept

Our top choices for Southern Illinois hotels with a spa

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A hotel room with a bed, desk, chair, TV, and a small kitchenette area.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.
An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

1. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
  • Luxurious spa sanctuary awaits with full-service treatments and indoor pool in this centrally located hotel.
€99
includes taxes & fees
10 Sept - 11 Sept
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A dining area with a wooden table and chairs, a small Christmas tree, and a window with curtains.
A dining area with a red wall, a large quilt, and Christmas decorations. There is a window with a view of the outside.
A bedroom with a large bed, a nightstand with a lamp, a chair, and a framed picture on the wall.

2. Arthur's Country Inn

Arthur's Country Inn
Arthur
€115
includes taxes & fees
7 Sept - 8 Sept
Arthur's Country Inn
A modern spa with a curved reception desk, a large mirror, and a decorative water feature.
A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A bar area with multiple seating arrangements, a stage, and a chandelier.

3. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
€172
includes taxes & fees
21 Sept - 22 Sept
Ameristar Casino Resort and Spa
A bathroom with a white sink, dark wooden door, and a shower area with striped glass walls.
A room with a bed, a nightstand with a lamp, a painting on the wall, and a radiator.
A room with a green armchair, a round table, a lamp, and a mirror on the wall.
A well-lit lobby with a chandelier, seating area, and decorative plants.

4. Truitt Hotel

Truitt Hotel
Lafayette Square
€176
includes taxes & fees
7 Sept - 8 Sept
Truitt Hotel
A two-story house with a front porch, a brick foundation, and a gabled roof.
A dining room with a round table set for six, surrounded by upholstered chairs. A vase with flowers and an American flag is on the table.
A traditional interior with a wooden staircase, a desk with a computer, and a red chair.
A kitchen with white cabinets, granite countertops, a stainless steel sink, a stove, and a microwave.

5. 1895 Washington Hotel

1895 Washington Hotel
Paducah
  • Unwind in a Victorian sanctuary with relaxing reflexology and soothing hydrotherapy treatments for total rejuvenation.
€100
includes taxes & fees
22 Sept - 23 Sept
1895 Washington Hotel
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."
A modern bathroom with a bathtub, a vanity with a mirror, and a shower area.
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.

6. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
€149
includes taxes & fees
27 Sept - 28 Sept
21C Museum Hotel St Louis
A couple relaxing by a window overlooking a bridge and water.
A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.
A modern hotel lobby with a glass facade, seating area, and a staircase.
A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.

7. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
€378
includes taxes & fees
7 Sept - 8 Sept
Four Seasons Hotel St Louis
A modern kitchen with wooden cabinets, a central island, and framed artwork on the walls.
An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.
An outdoor seating area with modern furniture, a bar, and large windows offering views of a cityscape.
A couple standing on a balcony with a cityscape view.

8. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
€552
includes taxes & fees
20 Sept - 21 Sept
The Ritz-Carlton, St. Louis
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Choose what matters most at spa hotels in Southern Illinois

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Southern Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

10/10 Excellent
"Excellent"
Matthew 2-night trip
Posted 5 hours ago
Drury Plaza Hotel Mt. Vernon
Comfort Suites Mount Vernon

Comfort Suites Mount Vernon

10/10 Excellent
"Excellent"
Van 1-night trip
Posted 1 day ago
Comfort Suites Mount Vernon
Country Inn & Suites by Radisson, Effingham, IL

Country Inn & Suites by Radisson, Effingham, IL

10/10 Excellent
"Clean comfortable room and a great breakfast."
Larry 1-night trip
Posted 1 day ago
Country Inn & Suites by Radisson, Effingham, IL
Quality Inn O'Fallon - St. Louis - Shiloh

Quality Inn O'Fallon - St. Louis - Shiloh

10/10 Excellent
"Location great"
Laura 1-night trip
Posted 1 day ago
Quality Inn O'Fallon - St. Louis - Shiloh

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