A public park with a fountain featuring bronze sculptures of mythological figures, surrounded by trees and a large building in the background.

Downtown St. Louis Hotel Guide - Boutique Hotels in Downtown St. Louis, St. Louis

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Downtown St. Louis Boutique Hotels

This weekend
6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov

Our top choices for Downtown St. Louis boutique hotels

A modern lobby with a staircase, seating area, and wall-mounted artwork.

1. Moonrise Hotel

Moonrise Hotel
4.0 star property
10.1 km from Downtown St. Louis
9.0 out of 10, Wonderful, (2,049 reviews)
"Cool hotel!"
United States
Rebecca
The price is €158
includes taxes & fees
18 Nov - 19 Nov
Moonrise Hotel
A grand building with a fountain in front.

2. The Cheshire

The Cheshire
4.0 star property
10.3 km from Downtown St. Louis
8.8 out of 10, Excellent, (1,006 reviews)
"Fantastic hotel, clean and nice rooms, great breakfast and location"
United States
Matthew
The price is €158
includes taxes & fees
29 Nov - 30 Nov
The Cheshire
A traditional Tudor-style building with a black awning labeled "28 Sally's Inn."

3. Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Seven Gables, St. Louis West, a Tribute Portfolio Hotel
3.5 star property
13.4 km from Downtown St. Louis
8.4 out of 10, Very good, (603 reviews)
"I always stay at the Seven Gables Inn while visiting St. Louis - fantastic, walkable neighborhood, for central STL, including vintage shopping & dining options. The boutique hotel is very ‘Old St. Louis’ with extremely modern, comfortable, quiet and safe rooms."
United States
Jennifer
The price is €164
includes taxes & fees
15 Nov - 16 Nov
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Downtown St. Louis Hotel Reviews

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

8/10 Good
"It’s a beautiful hotel. Was clean and nicely maintained. Not much in the way of amenities. No vending machines or store to get snacks or drinks. Valet didn’t offer to help with luggage at all, just got the car. No help with luggage, no tip."
Tracy 1-night trip
Posted 2 days ago
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Le Meridien St. Louis Downtown

Le Meridien St. Louis Downtown

8/10 Good
"The hotel was nice on the inside. My room was clean and the staff were nice and helpful. I did receive a room that was missing the cover to the door lock. The light in the room was really dark. I did ask for a late check out, however on check out day I returned to my room to pick up my stuff and the door was pried open and no one was in sight. Nothing was missing and The hotel was almost empty so I wasn’t really worried but that was unsettling. The front desk informed me that I had been checked out."
Corey 1-night trip
Posted 12 days ago
Le Meridien St. Louis Downtown

Frequently asked questions

What's there to see and do in Downtown St. Louis?
Visitors speak positively about this destination's acclaimed theatres, great live music and top museums. Activities and attractions to experience around Downtown St. Louis include St. Louis Union Station, Museum at the Gateway Arch and Cardinals Hall of Fame and Museum. You might also want to see spots like St. Louis Zoo, Old Courthouse and Gateway Arch National Park during your trip.
What's the best way to get to my boutique hotel in Downtown St. Louis?
You have a few options for travelling to and around Downtown St. Louis. The nearest major airport is Lambert-St. Louis International Airport (STL), which is located 12.5 mi (20.1 km) away. Nearby metro stations include 8th and Pine Station, Stadium Station and Convention Center Station.

Explore a world of travel with Expedia