
Southeast Minnesota Holidays
- Plan, book, travel with confidence
Better together
Save up to €185 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Where to stay in Southeast Minnesota
Find the best Southeast Minnesota areas and neighborhoods for the activities you enjoy most. Learn more about Southeast Minnesota

Downtown Rochester
2 out of top 10 points of interest in this area
If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Art Center are top sights worth seeing.
Top hotels in Southeast Minnesota

Kahler Grand Hotel
20 2nd Ave Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
The price is €135 per night from 28 Aug to 29 Aug
€135
28 Aug - 29 Aug
includes taxes & fees
8.2/10 Very Good! (1,534 reviews)
"Bery good but parking ito unload still a problem. Basic room has only desk chair and desk does not have light/-hard to work in room. But still the best location"
Reviewed on 23 Aug 2025

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
4353 Canal Pl SE, Rochester, MN
Fully refundableReserve now, pay when you stay
The price is €71 per night from 31 Aug to 1 Sept
€71
31 Aug - 1 Sept
includes taxes & fees
7.2/10 Good! (1,002 reviews)
Okay stay
"Hotel was clean. Sink drain not working. Fire alarm for faulty sensor sent everyone outdoors at 2330 hrs. Mgmt was apologetic."
Reviewed on 21 Aug 2025

Spark by Hilton Rochester South
4165 Maine Ave SE, Rochester, MN
Fully refundableReserve now, pay when you stay
The price is €72 per night from 7 Sept to 8 Sept
€72
7 Sept - 8 Sept
includes taxes & fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit

Winona State University
Take a campus tour or just explore the area of Winona State University during your trip to Winona. Stroll along the riverfront or experience the area's museums.
Mayo Clinic
If Mayo Clinic is what brings you to town, hopefully you'll have a chance to explore more of Rochester.
Regional Sports Center
Catch an event at Regional Sports Center during your trip to Rochester. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
Frequently asked questions
More trip options
Expedia's Latest Trends
Flights
Cars
Activities
Packages
Holiday Rentals
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.