Santa Lucia Hotels

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Lucia hotels

Hotel L'Orologio Roma

4.0 star property
Rome City Centre
9.6 out of 10, Exceptional, (421)
"Super friendly staff great hotel great location "
Canada
Jack
The price is €285
includes taxes & fees
6 Jan - 7 Jan 2026
Hotel L'Orologio Roma

River Palace Hotel

4.0 star property
Municipio I
9.0 out of 10, Wonderful, (1002)
"Excellent place"
Mexico
Dulce
River Palace Hotel

Hotel Diocleziano

4.0 star property
Rome City Centre
9.4 out of 10, Exceptional, (1001)
"Great staff and location. Very good quality hotel for a reasonable price. "
United States
Anne
The price is €124
includes taxes & fees
9 Jan - 10 Jan 2026
Hotel Diocleziano

Hotel Pacific Roma

3.0 star property
Vatican
9.0 out of 10, Wonderful, (818)
"Clean, great breakfast, friendly welcoming staff."
United States
Edward
Hotel Pacific Roma

The Republic Hotel

4.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (1124)
" A very nice clean hotel in a perfect location with very friendly staff and excellent services "
United States
TAMER SAMEH METWALLY
The price is €160
includes taxes & fees
19 Dec - 20 Dec
The Republic Hotel

Massimi City Garden Hotel

4.0 star property
Trionfale
9.2 out of 10, Wonderful, (190)
"The room was refreshed every day and the staff was really helpful. Great food. Thanks"
United States
Silvia M
Massimi City Garden Hotel

Mama Shelter Roma

4.0 star property
Vatican
9.0 out of 10, Wonderful, (895)
"Very nice bedding and comfortable bed. Room always clean and staff are very friendly."
United States
Irma
The price is €142
includes taxes & fees
4 Jan - 5 Jan 2026
Mama Shelter Roma

Hotel Gregoriana

3.0 star property
Rome City Centre
9.4 out of 10, Exceptional, (1005)
"Friendly staff, clean rooms, very private, superb location."
Canada
Tara
Hotel Gregoriana

Hotel Dei Mellini

4.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (1005)
"Fantastic location, beautifully clean, lovely breakfast, good restaurants nearby, quiet neighbourhood within walking distance of key sites. "
United Kingdom
Andrew J
The price is €248
includes taxes & fees
22 Dec - 23 Dec
Hotel Dei Mellini

The Social Hub Rome

4.0 star property
Tiburtino
9.2 out of 10, Wonderful, (521)
"Amazing stay! "
United States
Rashid Amin
The price is €86
includes taxes & fees
14 Dec - 15 Dec
The Social Hub Rome

Donna Camilla Savelli – VRetreats

4.0 star property
Rome City Centre
9.4 out of 10, Exceptional, (1000)
"Beautiful hotel"
United States
Jeffrey
The price is €163
includes taxes & fees
6 Jan - 7 Jan 2026
Donna Camilla Savelli – VRetreats

Hotel La Rovere

4.0 star property
Rome City Centre
9.0 out of 10, Wonderful, (686)
"Friendly staff, great breakfast buffet, convenient location to Vatican, Travis Fountain, the castle, Spanish steps, and shopping places."
United States
Ha
The price is €130
includes taxes & fees
14 Dec - 15 Dec
Hotel La Rovere

Hotel Imperiale by OMNIA hotels

4.0 star property
Rome City Centre
9.6 out of 10, Exceptional, (205)
"Spotless clean room and very cordial and helpful staff!"
United States
Maria
The price is €218
includes taxes & fees
18 Dec - 19 Dec
Hotel Imperiale by OMNIA hotels

Hotel Splendide Royal - The Leading Hotels of the World

5.0 star property
Rome City Centre
9.4 out of 10, Exceptional, (1002)
"Beautiful hotel, with a great location. Super clean and friendly staff. Had an amazing stay"
Canada
Julia
Hotel Splendide Royal - The Leading Hotels of the World

Hotel Marcantonio Rome

2.0 star property
Rome City Centre
8.4 out of 10, Very good, (1011)
"Great and inexpensive and has at you need "
United States
Oksana
The price is €76
includes taxes & fees
18 Dec - 19 Dec
Hotel Marcantonio Rome

Hotel Artemide

4.0 star property
Rome City Centre
9.8 out of 10, Exceptional, (1007)
"We had a great stay!"
United States
Terry
The price is €171
includes taxes & fees
18 Dec - 19 Dec
Hotel Artemide

The Hive Hotel

4.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (1712)
"Very enjoyable stay "
United States
John
The price is €125
includes taxes & fees
14 Dec - 15 Dec
The Hive Hotel

The Independent Hotel

4.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (1000)
"Helpful staff, good breakfast, clean and comfortable rooms"
United Kingdom
Nova
The price is €167
includes taxes & fees
6 Jan - 7 Jan 2026
The Independent Hotel

UNA Hotels Decò Roma

4.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (1526)
"The staff was great, the Breakfast was delicious, the The room was spotless and for me close to the termine is perfect "
United States
Norma
The price is €125
includes taxes & fees
7 Jan - 8 Jan 2026
UNA Hotels Decò Roma

Adesso Hotel

4.0 star property
Nomentano
9.4 out of 10, Exceptional, (727)
"Clean, good breakfast, friendly staff "
United States
Galyna
Adesso Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Santa Lucia Hotel Reviews

More cheap stays in Santa Lucia

Frequently asked questions

Where is the best place for a stay in Santa Lucia?
Located 10.1 mi (16.3 km) from the heart of Santa Lucia, Napoleon Hotel is a top choice for your stay, based on our traveller data. Two other choices for your trip to the area are Hotel Quirinale and The Hive Hotel. See all available top hotels, or vacation rentals in Santa Lucia.
What are some of the best holiday rentals that Santa Lucia has to offer?
Oriana Homèl Roma: This holiday home rental outside of Santa Lucia is in the city centre, and equipped with air conditioning and free WiFi to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop and a microwave. See all vacation rentals in Santa Lucia.
If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Lucia.
What is staying in Santa Lucia like?
Visitors will definitely enjoy all that Santa Lucia has to offer. Spanish Steps, Trevi Fountain and Colosseum are some of the top sights around the area. In Santa Lucia, there are 3 hotels and other accommodation options to choose from. Find out more about Santa Lucia.
What should I see while I'm in Santa Lucia?
Spanish Steps, Trevi Fountain and Colosseum are some of the notable places to visit in the surrounding area. You'll also find Piazza Navona and Piazza di Spagna in the area. Take a look at what more there is to see and do in Expedia's Santa Lucia guide.
What's the seasonal weather in Santa Lucia?
The hottest months are usually August and July, with an average temperature of 23°C, while the coldest months are January and February, with an average of 7°C. Average annual precipitation for Santa Lucia is 1047 mm.

Explore a world of travel with Expedia