Mission District Hotel Guide - Boutique Hotels in Mission District, San Francisco

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Check availability on Mission District Boutique Hotels

Tonight
24 Dec - 25 Dec
Tomorrow
25 Dec - 26 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Our top choices for Mission District boutique hotels

Indoor pool
Berkeley City Club

Berkeley City Club

Berkeley City Club
2.5 star property
Telegraph District
8.8 out of 10, Excellent, (696)
"Wonderful, beautiful, old world hotel, right in the heart of bustling Berkeley. "
United States
Peter
Berkeley City Club
Games room
Hotel Zephyr San Francisco

Hotel Zephyr San Francisco

Hotel Zephyr San Francisco
4.0 star property
Fisherman's Wharf
8.6 out of 10, Excellent, (2341)
"Great decor and really great location"
United States
Jose
The price is €155
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Zephyr San Francisco
Exterior
Hotel Emblem San Francisco

Hotel Emblem San Francisco

Hotel Emblem San Francisco
4.0 star property
Union Square
9.4 out of 10, Exceptional, (1004)
"Great place to stay when visiting the City - will return again!"
United States
Chris
The price is €146
includes taxes & fees
2 Jan - 3 Jan 2026
Hotel Emblem San Francisco
Lobby
The Clancy, Autograph Collection by Marriott

The Clancy, Autograph Collection by Marriott

The Clancy, Autograph Collection by Marriott
4.0 star property
Downtown San Francisco
9.2 out of 10, Wonderful, (1005)
"Very professional staff! Central located walking distance to everything!"
United States
Edmundo
The price is €199
includes taxes & fees
1 Jan - 2 Jan 2026
The Clancy, Autograph Collection by Marriott
Front of property – evening/night
Hotel Abri - Union Square

Hotel Abri - Union Square

Hotel Abri - Union Square
3.5 star property
Union Square
8.6 out of 10, Excellent, (1000)
"Very nice hotel"
United States
Mariam
The price is €134
includes taxes & fees
2 Jan - 3 Jan 2026
Hotel Abri - Union Square
Room (Private Apartment)
The Clift Royal Sonesta San Francisco

The Clift Royal Sonesta San Francisco

The Clift Royal Sonesta San Francisco
4.0 star property
Union Square
9.2 out of 10, Wonderful, (1367)
"Staff was amazing. The rooms felt clean and the hotel was very well maintained."
United States
Misty
The price is €181
includes taxes & fees
29 Dec - 30 Dec
The Clift Royal Sonesta San Francisco
Lobby
Warwick San Francisco

Warwick San Francisco

Warwick San Francisco
4.0 star property
Union Square
8.2 out of 10, Very good, (1001)
"Room was very nice! Staff was wonderful! "
United States
Brian
The price is €136
includes taxes & fees
25 Dec - 26 Dec
Warwick San Francisco
Meeting facility
The Barnes San Francisco, Tapestry Collection by Hilton

The Barnes San Francisco, Tapestry Collection by Hilton

The Barnes San Francisco, Tapestry Collection by Hilton
4.0 star property
Union Square
8.2 out of 10, Very good, (769)
"Wonderful Stay, Room was Clean. Close to Union Square. Would Stay Here again. "
United States
Raquel
The price is €131
includes taxes & fees
25 Dec - 26 Dec
The Barnes San Francisco, Tapestry Collection by Hilton
Exterior
Argonaut Hotel

Argonaut Hotel

Argonaut Hotel
4.5 star property
Fisherman's Wharf
9.4 out of 10, Exceptional, (1209)
"Absolutely amazing hotel!"
United States
Alicia
The price is €234
includes taxes & fees
25 Dec - 26 Dec
Argonaut Hotel
Lobby sitting area
The Marker Union Square San Francisco

The Marker Union Square San Francisco

The Marker Union Square San Francisco
4.0 star property
Union Square
9.0 out of 10, Wonderful, (1118)
"The staff was so fabulous, the hotel is gorgeous, and we are already having the best time!"
United States
Faith
The price is €139
includes taxes & fees
29 Dec - 30 Dec
The Marker Union Square San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mission District Hotel Reviews

Hotel Zoe Fisherman's Wharf

Hotel Zoe Fisherman's Wharf

10/10 Excellent
"Staff were very nice, friendly, and accommodating. Room was very clean"
Hilary 3-night trip
Posted 22 hours ago
Hotel Zoe Fisherman's Wharf

Frequently asked questions

What's there to see and do in Mission District?
The bars is one thing to enjoy while you're in the area. Favorite activities and sights around Mission District include Chase Center, Oracle Park and Pier 39. You might also want to see places such as San Francisco Bay, SOMA Pilipinas and SF Armory during your trip.
What's the best way to get to my boutique hotel in Mission District?
You have a few options for getting to Mission District. The closest major airport is San Francisco International Airport (SFO), which is located 10 mi (16.1 km) away. Take advantage of metro transport at 16th Street Mission Station, 24th Street Mission Station and Right Of Way/20th St Stop.

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