- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Otay Mesa LGBT-friendly hotels

1. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHGOtay Mesa
8.4 out of 10, Very good, (1,960 reviews)
The price is €134
includes taxes & fees
13 Dec - 14 Dec

2. La Quinta Inn by Wyndham San Diego Chula Vista
La Quinta Inn by Wyndham San Diego Chula VistaChula Vista
8.6 out of 10, Excellent, (1,801 reviews)
The price is €103
includes taxes & fees
29 Nov - 30 Nov

3. Hampton Inn & Suites Imperial Beach San Diego
Hampton Inn & Suites Imperial Beach San DiegoMar Vista
9.4 out of 10, Exceptional, (1,000 reviews)
The price is €131
includes taxes & fees
22 Nov - 23 Nov

4. Residence Inn by Marriott San Diego Chula Vista
Residence Inn by Marriott San Diego Chula VistaOtay Ranch
9.4 out of 10, Exceptional, (646 reviews)
The price is €184
includes taxes & fees
22 Nov - 23 Nov

5. Holiday Inn Express San Diego South - Chula Vista by IHG
Holiday Inn Express San Diego South - Chula Vista by IHGChula Vista
9.4 out of 10, Exceptional, (1,659 reviews)
The price is €145
includes taxes & fees
6 Dec - 7 Dec

6. Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway HotelNational City
9.2 out of 10, Wonderful, (4,236 reviews)
The price is €125
includes taxes & fees
22 Nov - 23 Nov

7. Days Inn by Wyndham Chula Vista/San Diego
Days Inn by Wyndham Chula Vista/San DiegoChula Vista
7.0 out of 10, Good, (1,328 reviews)
The price is €84
includes taxes & fees
18 Nov - 19 Nov

8. Gaylord Pacific Resort & Convention Center
Gaylord Pacific Resort & Convention CenterChula Vista
8.8 out of 10, Excellent, (706 reviews)
The price is €277
includes taxes & fees
15 Dec - 16 Dec

9. Sycuan Casino Resort
Sycuan Casino ResortEl Cajon
9.4 out of 10, Exceptional, (2,231 reviews)
The price is €101
includes taxes & fees
14 Dec - 15 Dec

10. Crowne Plaza San Diego - Mission Valley by IHG
Crowne Plaza San Diego - Mission Valley by IHGMission Valley
8.4 out of 10, Very good, (1,514 reviews)
The price is €115
includes taxes & fees
30 Nov - 1 Dec
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels in Otay Mesa
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG | 8.4 Very good 1,960 reviews | View | ||||||
![]() La Quinta Inn by Wyndham San Diego Chula Vista | 8.6 Excellent 1,801 reviews | View | ||||||
![]() Hampton Inn & Suites Imperial Beach San Diego | 9.4 Exceptional 1,000 reviews | View | ||||||
![]() Residence Inn by Marriott San Diego Chula Vista | 9.4 Exceptional 646 reviews | View | ||||||
![]() Holiday Inn Express San Diego South - Chula Vista by IHG | 9.4 Exceptional 1,659 reviews | View |



































