5 Star Hotels in Southeast Missouri, Missouri

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Check availability on Southeast Missouri 5 Star Hotels

Tonight
7 Jul - 8 Jul
Tomorrow
8 Jul - 9 Jul
This weekend
11 Jul - 13 Jul
Next weekend
18 Jul - 20 Jul

Top Southeast Missouri 5 Star Hotels

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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Southeast Missouri.
Urban Lofts

Urban Lofts

104 North Jackson Street, Perryville, MO
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Southeast Missouri

Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from Sam A. Baker State Park to K Bridge Recreation Area.

See all hotels in Southeast Missouri

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Southeast Missouri?
The amount you pay for a 5-star hotel in Southeast Missouri depends on things like when you want to go and the length of your trip. An insider tip for bagging an awesome deal? Use our pricing filters to check out all of the available options for your selected dates.

  • Search for the lowest price per night

What makes a hotel 5 stars in Southeast Missouri?
Outstanding guest service is the foundation of every 5-star hotel in Southeast Missouri. From the moment you enter the lobby, staff are at your beck and call, whether offering luggage assistance and storage or providing in-room massage treatments. Plus, hotels have to feature superior conveniences to qualify for a 5-star rating. These can include luxury baths, an on-site spa, pools, gastronomic restaurants and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Southeast Missouri?
Find a luxurious retreat that includes your room, meals, activities and entertainment in Southeast Missouri with the help of Expedia's filters. Search for resorts rated 5 stars and click on the "All inclusive" filter. Have a look at what's included in the price. That way, you'll be ready to maximize all the perks on offer when you get there.