Business Hotels in Mexico and Central America

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Top Cities in Mexico and Central America

Check availability on Mexico and Central America Business Hotels

Next weekend
In two weeks

Our top choices for Mexico and Central America business-friendly hotels

Hyatt Place Panama City/Downtown

Hyatt Place Panama City/Downtown
Panama City
8.6 out of 10, Excellent, (1000)
"Horrible. The establishment was closed (August 2021) when we arrived. The hotel charged my credit card only to find out when we arrived, the hotel was empty and abandoned. Never again!"
United States
John
Hyatt Place Panama City/Downtown

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (4690)
"Awesome great place to stay "
United States
Herbert
The price is €103
includes taxes & fees
13 Jan - 14 Jan 2026
Hotel Riu Plaza Panama

Galeria Plaza Reforma

Galeria Plaza Reforma
4.0 star property
Reforma
9.4 out of 10, Exceptional, (3202)
"Clean room, staff was amazing. "
United States
Manuel Ramirez
The price is €138
includes taxes & fees
22 Dec - 23 Dec
Galeria Plaza Reforma

InterContinental Presidente Mexico City by IHG

InterContinental Presidente Mexico City by IHG
4.0 star property
Polanco
9.4 out of 10, Exceptional, (2096)
"The best place to stay! "
United States
Mario Perez
The price is €252
includes taxes & fees
9 Jan - 10 Jan 2026
InterContinental Presidente Mexico City by IHG

Sheraton Maria Isabel Mexico City Reforma

Sheraton Maria Isabel Mexico City Reforma
4.0 star property
Reforma
9.2 out of 10, Wonderful, (2134)
"Very nice hotel. I really enjoyed my stay there."
United States
Rina Vazquez
The price is €144
includes taxes & fees
4 Jan - 5 Jan 2026
Sheraton Maria Isabel Mexico City Reforma

Hyatt Regency Mexico City

Hyatt Regency Mexico City
5.0 star property
Polanco
9.4 out of 10, Exceptional, (1337)
"Beautiful location hotel staff "
United States
Rajat
The price is €232
includes taxes & fees
17 Jan - 18 Jan 2026
Hyatt Regency Mexico City

Barceló Guatemala City

Barceló Guatemala City
4.5 star property
Zona 9
9.2 out of 10, Wonderful, (3112)
"Friendly staff , wonderful beds. Breakfast was great and large variety of foods. "
United States
Parker
The price is €78
includes taxes & fees
6 Jan - 7 Jan 2026
Barceló Guatemala City

Camino Real Aeropuerto Mexico

Camino Real Aeropuerto Mexico
4.0 star property
Venustiano Carranza
8.8 out of 10, Excellent, (11889)
"Great option to stay close the airport"
United States
Alexandra
The price is €129
includes taxes & fees
17 Jan - 18 Jan 2026
Camino Real Aeropuerto Mexico

Barceló México Reforma

Barceló México Reforma
4.5 star property
Reforma
9.4 out of 10, Exceptional, (5082)
"Great hotel!"
United States
Alma
The price is €125
includes taxes & fees
5 Jan - 6 Jan 2026
Barceló México Reforma

Novotel Panama City

Novotel Panama City
4.0 star property
Bella Vista
9.2 out of 10, Wonderful, (1026)
"Great service, big room, solid breakfasts.. all at good price."
Canada
Nicholas
The price is €99
includes taxes & fees
21 Dec - 22 Dec
Novotel Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Mexico and Central America Hotel Reviews